2-(R)-benzoyloxymethyl-4-(R)-(N-benzoyl-5-fluorocytosin-1-yl)-1,3-oxathiolane

Base Information

Chemical Name:2-(R)-benzoyloxymethyl-4-(R)-(N-benzoyl-5-fluorocytosin-1-yl)-1,3-oxathiolane
CAS No.:1137664-42-6
Molecular Formula:C₂₂H₁₈FN₃O₅S
Molecular Weight:455.466
Hs Code.:

Synonyms:2-(R)-benzoyloxymethyl-4-(R)-(N-benzoyl-5-fluorocytosin-1-yl)-1,3-oxathiolane

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(R)-benzoyloxymethyl-4-(R)-(N-benzoyl-5-fluorocytosin-1-yl)-1,3-oxathiolane

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Technology Process of 2-(R)-benzoyloxymethyl-4-(R)-(N-benzoyl-5-fluorocytosin-1-yl)-1,3-oxathiolane

There total 2 articles about 2-(R)-benzoyloxymethyl-4-(R)-(N-benzoyl-5-fluorocytosin-1-yl)-1,3-oxathiolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

: 2-(R)-benzoyloxymethyl-4-(R,S)-(N-benzoyl-5-fluorocytosin-1-yl)-1,3-oxathiolane

: 1137664-42-6
2-(R)-benzoyloxymethyl-4-(R)-(N-benzoyl-5-fluorocytosin-1-yl)-1,3-oxathiolane

Guidance literature:: In methanol; Purification / work up; Heating / reflux;

Reference yield:

: 478704-21-1
2-(S)-benzoyloxymethyl-1,3-oxathiolane-S-oxide

: 2-(R)-benzoyloxymethyl-1,3-oxathiolane-S-oxide

: 10357-07-0
N-benzoyl-5-fluorocytosine

: 2-(R)-benzoyloxymethyl-4-(S)-(N-benzoyl-5-fluorocytosin-1-yl)-1,3-oxathiolane

: 1137664-44-8
2-(S)-benzoyloxymethyl-4-(S)-(N-benzoyl-5-fluorocytosin-1-yl)-1,3-oxathiolane

: 1137664-42-6
2-(R)-benzoyloxymethyl-4-(R)-(N-benzoyl-5-fluorocytosin-1-yl)-1,3-oxathiolane

: 2-(S)-benzoyloxymethyl-4-(R)-(N-benzoyl-5-fluorocytosin-1-yl)-1,3-oxathiolane

Guidance literature:: 2-(S)-benzoyloxymethyl-1,3-oxathiolane-S-oxide; 2-(R)-benzoyloxymethyl-1,3-oxathiolane-S-oxide; With trimethylsilyl iodide; triethylamine; In dichloromethane; at -50 - -35 ℃; for 1h;

N-benzoyl-5-fluorocytosine; copper dichloride; In dichloromethane; at -50 - 20 ℃;

With water; sodium hydrogencarbonate; In dichloromethane; for 0.0833333h;