2-oxo-2H-3-(3-aminobenzyl)-4-methyl-6-chloro-7-hydroxy-1-benzopyran

Base Information

• Chemical Name: 2-oxo-2H-3-(3-aminobenzyl)-4-methyl-6-chloro-7-hydroxy-1-benzopyran
• CAS No.: 946127-00-0
• Molecular Formula: C₁₇H₁₄ClNO₃
• Molecular Weight: 315.756
• Mol file: 946127-00-0.mol

Synonyms:2-oxo-2H-3-(3-aminobenzyl)-4-methyl-6-chloro-7-hydroxy-1-benzopyran

Chemical Property of 2-oxo-2H-3-(3-aminobenzyl)-4-methyl-6-chloro-7-hydroxy-1-benzopyran

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-oxo-2H-3-(3-aminobenzyl)-4-methyl-6-chloro-7-hydroxy-1-benzopyran

There total 4 articles about 2-oxo-2H-3-(3-aminobenzyl)-4-methyl-6-chloro-7-hydroxy-1-benzopyran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-(3-nitrobenzyl)-7-hydroxy-4-methyl-6-chloro-2-oxo-2H-1-benzopyran (393812-71-0) → 2-oxo-2H-3-(3-aminobenzyl)-4-methyl-6-chloro-7-hydroxy-1-benzopyran (946127-00-0)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol; at 20 ℃;

DOI:10.1016/j.bmcl.2004.03.022

Reference yield:

4-Chlororesorcinol (95-88-5) → 2-oxo-2H-3-(3-aminobenzyl)-4-methyl-6-chloro-7-hydroxy-1-benzopyran (946127-00-0)

Guidance literature:

Multi-step reaction with 2 steps

1: aq. H₂SO₄ / 100 °C

2: H₂ / Pd/C / ethanol / 20 °C

With sulfuric acid; hydrogen; palladium on activated charcoal; In ethanol;

DOI:10.1016/j.bmcl.2004.03.022

Reference yield:

2-(3-nitrobenzyl)-3-oxo-butyric acid ethyl ester (393812-70-9) → 2-oxo-2H-3-(3-aminobenzyl)-4-methyl-6-chloro-7-hydroxy-1-benzopyran (946127-00-0)

Guidance literature:

Multi-step reaction with 2 steps

1: aq. H₂SO₄ / 100 °C

2: H₂ / Pd/C / ethanol / 20 °C

With sulfuric acid; hydrogen; palladium on activated charcoal; In ethanol;

DOI:10.1016/j.bmcl.2004.03.022

upstream raw materials:

3-(3-nitrobenzyl)-7-hydroxy-4-methyl-6-chloro-2-oxo-2H-1-benzopyran

4-Chlororesorcinol

2-(3-nitrobenzyl)-3-oxo-butyric acid ethyl ester