methyl (4S,2E)-2-benzyloxycarbonylamino-4,5-isopropylidenedioxy-2-pentanoate

Base Information

Chemical Name:methyl (4S,2E)-2-benzyloxycarbonylamino-4,5-isopropylidenedioxy-2-pentanoate
CAS No.:173327-94-1
Molecular Formula:C₁₇H₂₁NO₆
Molecular Weight:335.357
Hs Code.:

Synonyms:methyl (4S,2E)-2-benzyloxycarbonylamino-4,5-isopropylidenedioxy-2-pentanoate

Suppliers and Price of methyl (4S,2E)-2-benzyloxycarbonylamino-4,5-isopropylidenedioxy-2-pentanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl (4S,2E)-2-benzyloxycarbonylamino-4,5-isopropylidenedioxy-2-pentanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl (4S,2E)-2-benzyloxycarbonylamino-4,5-isopropylidenedioxy-2-pentanoate

There total 3 articles about methyl (4S,2E)-2-benzyloxycarbonylamino-4,5-isopropylidenedioxy-2-pentanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1191124-96-5
N-benzyloxycarbonyl-α-(diphenylphosphono)glycine methyl ester

: 15186-48-8
2,3-isopropylidene-glyceraldehyde

: 173327-94-1
methyl (4S,2E)-2-benzyloxycarbonylamino-4,5-isopropylidenedioxy-2-pentanoate

: 132970-32-2
methyl (4S,2Z)-2-benzyloxycarbonylamino-4,5-isopropylidenedioxy-2-pentanoate

Guidance literature:: N-benzyloxycarbonyl-α-(diphenylphosphono)glycine methyl ester; With 1,8-diazabicyclo[5.4.0]undec-7-ene; zinc(II) chloride; In tetrahydrofuran; diethyl ether; at 0 ℃; for 0.5h; Inert atmosphere;

2,3-isopropylidene-glyceraldehyde; In tetrahydrofuran; diethyl ether; at 20 ℃; for 16h; Reagent/catalyst; Temperature; Time; Overall yield = 92 %; stereoselective reaction; Inert atmosphere;
DOI:10.1002/ejoc.201300112

Reference yield:

: 114684-69-4
methyl 2-(benzyloxycarbonylamino)-2-(diethyloxyphosphoryl)acetate

: 1707-77-3
1,2:5,6-di-O-isopropylidene-D-mannitol

: 173327-94-1
methyl (4S,2E)-2-benzyloxycarbonylamino-4,5-isopropylidenedioxy-2-pentanoate

: 132970-32-2
methyl (4S,2Z)-2-benzyloxycarbonylamino-4,5-isopropylidenedioxy-2-pentanoate

Guidance literature:: With sodium periodate; tetrabutylammomium bromide; sodium hydrogencarbonate; potassium carbonate; Yield given. Multistep reaction. Yields of byproduct given; 1.) 1 h, 2.) CH₂Cl₂, RT, 4 h;
DOI:10.1246/bcsj.68.3151

Reference yield:

: 100945-15-1,88568-95-0
N-(benzyloxycarbonyl)phosphonoglycine trimethyl ester

: 15186-48-8
2,3-isopropylidene-glyceraldehyde

: 173327-94-1
methyl (4S,2E)-2-benzyloxycarbonylamino-4,5-isopropylidenedioxy-2-pentanoate

: 132970-32-2
methyl (4S,2Z)-2-benzyloxycarbonylamino-4,5-isopropylidenedioxy-2-pentanoate

Guidance literature:: With potassium tert-butylate; Yields of byproduct given; 1) -70 deg C, 15 min 2) a) -70 deg C, 0.5 h b) to 35 deg C, 4.5 h;
DOI:10.1055/s-1991-26378