9-acetyl-15-trans-(4-n-propylcyclohexyl)-16,17,18,19,20-pentanor-15-dehydroprostaglandin F_2α methyl ester

Base Information

• Chemical Name: 9-acetyl-15-trans-(4-n-propylcyclohexyl)-16,17,18,19,20-pentanor-15-dehydroprostaglandin F_2α methyl ester
• CAS No.: 117169-73-0
• Molecular Formula: C₂₇H₄₂O₆
• Molecular Weight: 462.627
• Mol file: 117169-73-0.mol

Synonyms:9-acetyl-15-trans-(4-n-propylcyclohexyl)-16,17,18,19,20-pentanor-15-dehydroprostaglandin F_2α methyl ester

Chemical Property of 9-acetyl-15-trans-(4-n-propylcyclohexyl)-16,17,18,19,20-pentanor-15-dehydroprostaglandin F_2α methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 9-acetyl-15-trans-(4-n-propylcyclohexyl)-16,17,18,19,20-pentanor-15-dehydroprostaglandin F_2α methyl ester

There total 11 articles about 9-acetyl-15-trans-(4-n-propylcyclohexyl)-16,17,18,19,20-pentanor-15-dehydroprostaglandin F_2α methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

9-acetyl-15-cis-(4-n-propylcyclohexyl)-16,17,18,19,20-pentanor-15-dehydroprostaglandin F2α methyl ester 11-tetrahydropyranyl ether (101691-34-3) → 9-acetyl-15-trans-(4-n-propylcyclohexyl)-16,17,18,19,20-pentanor-15-dehydroprostaglandin F2α methyl ester (117169-73-0) + 9-acetyl-15-cis-(4-n-propylcyclohexyl)-16,17,18,19,20-pentanor-15-dehydroprostaglandin F2α methyl ester (117169-73-0)

Guidance literature:

With acetic acid; In tetrahydrofuran; at 40 ℃; for 1.5h;

DOI:10.1248/cpb.36.1128

Reference yield: 92.0%

9-acetyl-15-cis-(4-n-propylcyclohexyl)-16,17,18,19,20-pentanor-15-dehydroprostaglandin F2α methyl ester 11-tetrahydropyranyl ether (101691-34-3) → 9-acetyl-15-trans-(4-n-propylcyclohexyl)-16,17,18,19,20-pentanor-15-dehydroprostaglandin F2α methyl ester (117169-73-0) + 9-acetyl-15-cis-(4-n-propylcyclohexyl)-16,17,18,19,20-pentanor-15-dehydroprostaglandin F2α methyl ester (117169-73-0)

Guidance literature:

With acetic acid; In tetrahydrofuran; at 40 ℃; for 1.5h;

DOI:10.1248/cpb.36.1128

Reference yield:

9-acetyl-15-trans-(4-n-propylcyclohexyl)-16,17,18,19,20-pentanor-15-dehydroprostaglandin F2α methyl ester 11-tetrahydropyranyl ether (101691-34-3,135559-33-0) → 9-acetyl-15-trans-(4-n-propylcyclohexyl)-16,17,18,19,20-pentanor-15-dehydroprostaglandin F2α methyl ester (117169-73-0)

Guidance literature:

With acetic acid; In tetrahydrofuran; at 40 ℃; for 1.5h;

DOI:10.1248/cpb.36.1128

upstream raw materials:

9-acetyl-15-trans-(4-n-propylcyclohexyl)-16,17,18,19,20-pentanor-15-dehydroprostaglandin F_2α methyl ester 11-tetrahydropyranyl ether

9-acetyl-15-cis-(4-n-propylcyclohexyl)-16,17,18,19,20-pentanor-15-dehydroprostaglandin F_2α methyl ester 11-tetrahydropyranyl ether

methyl (Z)-7-[(1R,2R,3R,5S)-5-acetoxy-2-formyl-3-(2-tetrahydropyranyloxy)cyclopentyl]-5-heptenate

methyl trans-4-n-propylcyclohexanecarboxylate

Downstream raw materials:

(Z)-7-[(1R,2R,3R,5S)-5-Acetoxy-2-[(E)-(S)-3-(4-propyl-cyclohexyl)-3-(tetrahydro-pyran-2-yloxy)-propenyl]-3-(tetrahydro-pyran-2-yloxy)-cyclopentyl]-hept-5-enoic acid methyl ester

9-deoxy-9β-tosyloxy-15-trans-(4-n-propylcyclohexyl)-16,17,18,19,20-pentanorprostaglandin F₂ methyl ester

15-trans-(4-α-propylcyclohexyl)-16,17,18,19,20-pentanorprostaglandin F_2α methyl ester

15-trans-(4-n-propylcyclohexyl)-16,17,18,19,20-pentanor-9-deoxy-6,9α-nitriloprostaglandin F₁ methyl ester