prop-2-yn-1-yl 3-phenylpropanoate

Base Information

• Chemical Name: prop-2-yn-1-yl 3-phenylpropanoate
• CAS No.: 23522-64-7
• Molecular Formula: C₁₂H₁₂O₂
• Molecular Weight: 188.226
• Mol file: 23522-64-7.mol

Synonyms:prop-2-yn-1-yl 3-phenylpropanoate

Chemical Property of prop-2-yn-1-yl 3-phenylpropanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of prop-2-yn-1-yl 3-phenylpropanoate

There total 9 articles about prop-2-yn-1-yl 3-phenylpropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

propargyl bromide (106-96-7) + 3-Phenylpropionic acid (501-52-0) → prop-2-yn-1-yl 3-phenylpropanoate (23522-64-7)

Guidance literature:

With potassium fluoride; tetra(n-butyl)ammonium hydrogensulfate; In tetrahydrofuran; at 20 ℃; for 3h;

DOI:10.1016/S0040-4039(01)02035-4

Reference yield: 92.0%

propargyl alcohol (107-19-7) + 3-Phenylpropionic acid (501-52-0) → prop-2-yn-1-yl 3-phenylpropanoate (23522-64-7)

Guidance literature:

With dmap; triethylamine; trichlorophosphate; In dichloromethane; at 20 ℃; for 2h;

DOI:10.1039/c3ra42887g

Reference yield: 88.0%

(E)-3-phenylpropenal (14371-10-9) + propargyl alcohol (107-19-7) → prop-2-yn-1-yl 3-phenylpropanoate (23522-64-7)

Guidance literature:

With triethylamine; 2-hydroxy-2-methylpropanenitrile; at 25 ℃; for 3h;

DOI:10.1016/j.tetlet.2005.09.173

upstream raw materials:

propargyl bromide

3-Phenylpropionic acid

(E)-3-phenylpropenal

propargyl alcohol