5,7-dihydroxy-6-(2-chloro-6-fluorophenyl)imidazo[1,2-a]pyrimidine DBN salt

Base Information

• Chemical Name: 5,7-dihydroxy-6-(2-chloro-6-fluorophenyl)imidazo[1,2-a]pyrimidine DBN salt
• CAS No.: 615269-36-8
• Molecular Formula: C₇H₁₂N₂*C₁₂H₇ClFN₃O₂
• Molecular Weight: 403.844
• Mol file: 615269-36-8.mol

Synonyms:5,7-dihydroxy-6-(2-chloro-6-fluorophenyl)imidazo[1,2-a]pyrimidine DBN salt

Chemical Property of 5,7-dihydroxy-6-(2-chloro-6-fluorophenyl)imidazo[1,2-a]pyrimidine DBN salt

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5,7-dihydroxy-6-(2-chloro-6-fluorophenyl)imidazo[1,2-a]pyrimidine DBN salt

There total 1 articles about 5,7-dihydroxy-6-(2-chloro-6-fluorophenyl)imidazo[1,2-a]pyrimidine DBN salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

diethyl (2-chloro-6-fluoro-phenyl)-malonate (190521-88-1) + 2-amino-1H-imidazole hydrochloride (52737-40-3,57575-96-9) → 5,7-dihydroxy-6-(2-chloro-6-fluorophenyl)imidazo[1,2-a]pyrimidine DBN salt (615269-36-8)

Guidance literature:

With DBN; In DMF (N,N-dimethyl-formamide); at 100 ℃; for 4h;

Reference yield:

5,7-dihydroxy-6-(2-chloro-6-fluorophenyl)imidazo[1,2-a]pyrimidine DBN salt (615269-36-8) → 5,7-dichloro-6-(2-chloro-6-fluorophenyl)imidazo[1,2-a]pyrimidine

Guidance literature:

With trichlorophosphate; for 10h; Heating / reflux;

upstream raw materials:

diethyl (2-chloro-6-fluoro-phenyl)-malonate

2-amino-1H-imidazole hydrochloride