Technology Process of C32H38N2O6
There total 3 articles about C32H38N2O6 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
N-ethyl-N,N-diisopropylamine;
In
acetonitrile;
at 20 ℃;
for 1h;
DOI:10.1021/ol300280s
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium hydride / tetrahydrofuran; mineral oil / 0.25 h / 0 - 20 °C
1.2: 1 h / 20 °C
2.1: n-butyllithium / tetrahydrofuran; hexane / 0.25 h / -78 - 0 °C
2.2: 3 h / -78 °C
3.1: N-ethyl-N,N-diisopropylamine / acetonitrile / 1 h / 20 °C
With
n-butyllithium; sodium hydride; N-ethyl-N,N-diisopropylamine;
In
tetrahydrofuran; hexane; acetonitrile; mineral oil;
1.1: Horner-Wadsworth-Emmons olefination / 1.2: Horner-Wadsworth-Emmons olefination / 2.2: Aza-Michael addition;
DOI:10.1021/ol300280s
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: palladium diacetate; potassium carbonate / isopropyl alcohol / 4 h / 70 °C
2.1: sodium hydride / tetrahydrofuran; mineral oil / 0.25 h / 0 - 20 °C
2.2: 1 h / 20 °C
3.1: n-butyllithium / tetrahydrofuran; hexane / 0.25 h / -78 - 0 °C
3.2: 3 h / -78 °C
4.1: N-ethyl-N,N-diisopropylamine / acetonitrile / 1 h / 20 °C
With
n-butyllithium; palladium diacetate; sodium hydride; potassium carbonate; N-ethyl-N,N-diisopropylamine;
In
tetrahydrofuran; hexane; isopropyl alcohol; acetonitrile; mineral oil;
1.1: Suzuki-Miyaura coupling / 2.1: Horner-Wadsworth-Emmons olefination / 2.2: Horner-Wadsworth-Emmons olefination / 3.2: Aza-Michael addition;
DOI:10.1021/ol300280s
