1-(4-(tert-Butyl)phenyl)-4-(4-hydroxypiperidin-1-yl)butan-1-one

Base Information

Chemical Name:1-(4-(tert-Butyl)phenyl)-4-(4-hydroxypiperidin-1-yl)butan-1-one
CAS No.:97928-18-2
Molecular Formula:C₁₉H₂₉NO₂
Molecular Weight:303.445
Hs Code.:2933399090
European Community (EC) Number:619-298-4
UNII:ZGA75UV2KC
DSSTox Substance ID:DTXSID70604271
Nikkaji Number:J766.888K
Wikidata:Q72502391
Mol file:97928-18-2.mol

Synonyms:97928-18-2;1-(4-(tert-Butyl)phenyl)-4-(4-hydroxypiperidin-1-yl)butan-1-one;1-[3-(4-TERT-BUTYLBENZOYL)PROPYL]-4-HYDROXYPIPERIDINE;1-(4-tert-butylphenyl)-4-(4-hydroxypiperidin-1-yl)butan-1-one;ZGA75UV2KC;1-[4-(1,1-dimethylethyl)phenyl]-4-(4-hydroxypiperidin-1-yl)butan-1-one;1-(4-(1,1-Dimethylethyl)phenyl)-4-(4-hydroxypiperidin-1-yl)butan-1-one;1-Butanone, 1-(4-(1,1-dimethylethyl)phenyl)-4-(4-hydroxy-1-piperidinyl)-;1-(3-(4-tert-butylbenzoyl)propyl)-4-hydroxypiperidine;Ebastine Imp. D (EP);1-[4-(1,1-Dimethylethyl)phenyl]-4-(4-hydroxypiperidin-1-yl)butan-1-one;Ebastine Related Compound D;Ebastine Impurity D;UNII-ZGA75UV2KC;SCHEMBL4350904;DTXSID70604271;AKOS015950926;AC-26761;A850795;1-[3-(4-tert-Butylbenzoyl)propyl]-4-hydroxypiperidine, AldrichCPR;Ebastine impurity D, European Pharmacopoeia (EP) Reference Standard

Suppliers and Price of 1-(4-(tert-Butyl)phenyl)-4-(4-hydroxypiperidin-1-yl)butan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-[3-(4-tert-Butylbenzoyl)propyl]-4-hydroxypiperidine
2g
$ 165.00

Sigma-Aldrich
Ebastine impurity D European Pharmacopoeia (EP) Reference Standard
y0000248
$ 179.00

Sigma-Aldrich
1-[3-(4-tert-Butylbenzoyl)propyl]-4-hydroxypiperidine Aldrich
1g
$ 80.60

Crysdot
1-(4-(tert-Butyl)phenyl)-4-(4-hydroxypiperidin-1-yl)butan-1-one 95+%
5g
$ 461.00

Chemenu
1-(4-(tert-butyl)phenyl)-4-(4-hydroxypiperidin-1-yl)butan-1-one 95%
5g
$ 436.00

Biosynth Carbosynth
1-[3-(4-tert-Butylbenzoyl)propyl]-4-hydroxypiperidine
500 mg
$ 145.00

Biosynth Carbosynth
1-[3-(4-tert-Butylbenzoyl)propyl]-4-hydroxypiperidine
1 g
$ 254.40

Biosynth Carbosynth
1-[3-(4-tert-Butylbenzoyl)propyl]-4-hydroxypiperidine
2 g
$ 462.50

Biosynth Carbosynth
1-[3-(4-tert-Butylbenzoyl)propyl]-4-hydroxypiperidine
10 g
$ 1528.80

Biosynth Carbosynth
1-[3-(4-tert-Butylbenzoyl)propyl]-4-hydroxypiperidine
5 g
$ 840.90

Total 34 raw suppliers

Chemical Property of 1-(4-(tert-Butyl)phenyl)-4-(4-hydroxypiperidin-1-yl)butan-1-one

Chemical Property:

Appearance/Colour:Off-White Solid
Melting Point:70-73 °C
Boiling Point:450.832 °C at 760 mmHg
PKA:14.87±0.20(Predicted)
Flash Point:226.455 °C
PSA：40.54000
Density:1.042 g/cm³
LogP:3.34160
Storage Temp.:Refrigerator
XLogP3:3.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:303.219829168
Heavy Atom Count:22
Complexity:345

Purity/Quality:

99.9% ^*data from raw suppliers

1-[3-(4-tert-Butylbenzoyl)propyl]-4-hydroxypiperidine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36
Safety Statements: 26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)C1=CC=C(C=C1)C(=O)CCCN2CCC(CC2)O
Uses Ebastine intermediate

Technology Process of 1-(4-(tert-Butyl)phenyl)-4-(4-hydroxypiperidin-1-yl)butan-1-one

There total 2 articles about 1-(4-(tert-Butyl)phenyl)-4-(4-hydroxypiperidin-1-yl)butan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%