7,10-di-O-[2-(chloroacetyl)]-13-[(4S,5R)-2-p-methoxyphenyl-4-phenyl-3-[(2-phenyl-2-trimethylsilyl)ethoxycarbonyl]-1,3-oxazolidinyl-5carbonyl]-10-deacetylbaccatin III

Base Information

Chemical Name:7,10-di-O-[2-(chloroacetyl)]-13-[(4S,5R)-2-p-methoxyphenyl-4-phenyl-3-[(2-phenyl-2-trimethylsilyl)ethoxycarbonyl]-1,3-oxazolidinyl-5carbonyl]-10-deacetylbaccatin III
CAS No.:632335-27-4
Molecular Formula:C₆₂H₆₉Cl₂NO₁₇Si
Molecular Weight:1199.22
Hs Code.:

7,10-di-O-[2-(chloroacetyl)]-13-[(4S,5R)-2-p-methoxyphenyl-4-phenyl-3-[(2-phenyl-2-trimethylsilyl)ethoxycarbonyl]-1,3-oxazolidinyl-5carbonyl]-10-deacetylbaccatin III

Synonyms:7,10-di-O-[2-(chloroacetyl)]-13-[(4S,5R)-2-p-methoxyphenyl-4-phenyl-3-[(2-phenyl-2-trimethylsilyl)ethoxycarbonyl]-1,3-oxazolidinyl-5carbonyl]-10-deacetylbaccatin III

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Chemical Property of 7,10-di-O-[2-(chloroacetyl)]-13-[(4S,5R)-2-p-methoxyphenyl-4-phenyl-3-[(2-phenyl-2-trimethylsilyl)ethoxycarbonyl]-1,3-oxazolidinyl-5carbonyl]-10-deacetylbaccatin III

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Technology Process of 7,10-di-O-[2-(chloroacetyl)]-13-[(4S,5R)-2-p-methoxyphenyl-4-phenyl-3-[(2-phenyl-2-trimethylsilyl)ethoxycarbonyl]-1,3-oxazolidinyl-5carbonyl]-10-deacetylbaccatin III

There total 1 articles about 7,10-di-O-[2-(chloroacetyl)]-13-[(4S,5R)-2-p-methoxyphenyl-4-phenyl-3-[(2-phenyl-2-trimethylsilyl)ethoxycarbonyl]-1,3-oxazolidinyl-5carbonyl]-10-deacetylbaccatin III which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 632335-27-4
7,10-di-O-[2-(chloroacetyl)]-13-[(4S,5R)-2-p-methoxyphenyl-4-phenyl-3-[(2-phenyl-2-trimethylsilyl)ethoxycarbonyl]-1,3-oxazolidinyl-5carbonyl]-10-deacetylbaccatin III

Guidance literature:

Reference yield: 82.0%

: 632335-27-4
7,10-di-O-[2-(chloroacetyl)]-13-[(4S,5R)-2-p-methoxyphenyl-4-phenyl-3-[(2-phenyl-2-trimethylsilyl)ethoxycarbonyl]-1,3-oxazolidinyl-5carbonyl]-10-deacetylbaccatin III

: 24424-99-5
di-tert-butyl dicarbonate

: 632335-31-0
7,10-di-O-(2-chlroacetyl)docetaxel

Guidance literature:: 7,10-di-O-[2-(chloroacetyl)]-13-[(4S,5R)-2-p-methoxyphenyl-4-phenyl-3-[(2-phenyl-2-trimethylsilyl)ethoxycarbonyl]-1,3-oxazolidinyl-5carbonyl]-10-deacetylbaccatin III; With tetrabutyl ammonium fluoride; In dichloromethane; at 25 - 30 ℃; for 0.5h;

di-tert-butyl dicarbonate; With sodium hydrogencarbonate; In toluene; at 25 - 30 ℃; for 3h;