(R)-2-(((S)-tert-butoxycarbonylamino)(4-methylphenyl)methyl)-2-cyanocyclopentanone

Base Information

• Chemical Name: (R)-2-(((S)-tert-butoxycarbonylamino)(4-methylphenyl)methyl)-2-cyanocyclopentanone
• CAS No.: 1023754-75-7
• Molecular Formula: C₁₉H₂₄N₂O₃
• Molecular Weight: 328.411
• Mol file: 1023754-75-7.mol

Synonyms:(R)-2-(((S)-tert-butoxycarbonylamino)(4-methylphenyl)methyl)-2-cyanocyclopentanone

Chemical Property of (R)-2-(((S)-tert-butoxycarbonylamino)(4-methylphenyl)methyl)-2-cyanocyclopentanone

Chemical Property:

Purity/Quality:

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Technology Process of (R)-2-(((S)-tert-butoxycarbonylamino)(4-methylphenyl)methyl)-2-cyanocyclopentanone

There total 1 articles about (R)-2-(((S)-tert-butoxycarbonylamino)(4-methylphenyl)methyl)-2-cyanocyclopentanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-oxocyclopentanecarbonitrile (2941-29-9,138260-51-2) + (E)-tert-butyl 4-methylbenzylidenecarbamate (743430-45-7) → (R)-2-(((S)-tert-butoxycarbonylamino)(4-methylphenyl)methyl)-2-cyanocyclopentanone (1023754-75-7) + 2-((tert-butoxycarbonylamino)(4-methylphenyl)methyl)-2-cyanocyclopentanone

Guidance literature:

(S)-N-(2-hydroxyphenyl)-2-salicyloylaminoisovaleramide; Sc(OiPr)3; In dichloromethane; at 0 ℃; for 12h;

DOI:10.1021/ja800326d

upstream raw materials:

2-oxocyclopentanecarbonitrile

(E)-tert-butyl 4-methylbenzylidenecarbamate