5-(1-Methoxy-2-methylpropan-2-YL)-1,2-oxazol-3-amine

Base Information

Chemical Name:5-(1-Methoxy-2-methylpropan-2-YL)-1,2-oxazol-3-amine
CAS No.:93509-70-7
Molecular Formula:C₈H₁₄N₂O₂
Molecular Weight:170.211
Hs Code.:
DSSTox Substance ID:DTXSID40537401
Wikidata:Q82412385
Mol file:93509-70-7.mol

Synonyms:93509-70-7;5-(1-METHOXY-2-METHYLPROPAN-2-YL)-1,2-OXAZOL-3-AMINE;5-(1-METHOXY-2-METHYLPROPAN-2-YL)ISOXAZOL-3-AMINE;5-(2-methoxy-1,1-dimethyl-ethyl)-isoxazol-3-ylamine;3-Isoxazolamine,5-(2-methoxy-1,1-dimethylethyl)-(9CI);SCHEMBL1013430;DTXSID40537401;ISFBSBAZSPGMSW-UHFFFAOYSA-N;AKOS006373510;G58645;EN300-7438018;A1-27041;3-amino-5-(1-(methoxymethyl)-1-methylethyl)-1,2-oxazole

Suppliers and Price of 5-(1-Methoxy-2-methylpropan-2-YL)-1,2-oxazol-3-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
5-(1-Methoxy-2-methylpropan-2-YL)-1,2-oxazol-3-amine
100mg
$ 608.00

A1 Biochem Labs
5-(2-Methoxy-1,1-dimethyl-ethyl)-isoxazol-3-ylamine 95%
5 g
$ 1500.00

Total 9 raw suppliers

Chemical Property of 5-(1-Methoxy-2-methylpropan-2-YL)-1,2-oxazol-3-amine

Chemical Property:

PSA：62.01000
LogP:1.11090
XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:170.105527694
Heavy Atom Count:12
Complexity:150

Purity/Quality:

98%min ^*data from raw suppliers

5-(1-Methoxy-2-methylpropan-2-YL)-1,2-oxazol-3-amine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(COC)C1=CC(=NO1)N

Technology Process of 5-(1-Methoxy-2-methylpropan-2-YL)-1,2-oxazol-3-amine

There total 3 articles about 5-(1-Methoxy-2-methylpropan-2-YL)-1,2-oxazol-3-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

: 90087-79-9
5-methoxy-4,4-dimethyl-3-oxopentanenitrile

: 93509-70-7
5-(1-methoxy-2-methylpropan-2-yl)isoxazol-3-amine

Guidance literature:: With hydroxylammonium sulfate; sodium hydroxide; In water monomer; at 100 ℃; for 0.5h;

Reference yield:

: 25307-88-4
methyl 3-methoxy-2,2-dimethylpropionate

: 93509-70-7
5-(1-methoxy-2-methylpropan-2-yl)isoxazol-3-amine

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / tetrahydrofuran; mineral oil / 15.75 h / 70 - 75 °C

2.1: hydroxyamino hydrochloride; sodium hydroxide / ethanol; water monomer / 22 h / 60 °C

2.2: 1 h / 80 °C

With hydroxyamino hydrochloride; sodium hydride; sodium hydroxide; In tetrahydrofuran; ethanol; water monomer; mineral oil;
DOI:10.1021/jm2009925

Reference yield:

: 14002-80-3
Methyl 2,2-dimethyl-3-hydroxypropionate

: 93509-70-7
5-(1-methoxy-2-methylpropan-2-yl)isoxazol-3-amine

Guidance literature:: Multi-step reaction with 3 steps

1.1: potassium hydroxide / dimethyl sulfoxide / 20 °C

2.1: lithium dipropan-2-ylazanide / tetrahydrofuran / 0.5 h / -78 °C

2.2: -78 - 20 °C

3.1: hydroxyamino hydrochloride; sodium hydroxide / ethanol; water monomer / 80 °C

With hydroxyamino hydrochloride; potassium hydroxide; sodium hydroxide; lithium dipropan-2-ylazanide; In tetrahydrofuran; ethanol; water monomer; dimethyl sulfoxide;