2-[(2,3,4-trihydroxyphenyl)methylene]-N-phenylhydrazine carbothioamsolidide

Base Information

• Chemical Name: 2-[(2,3,4-trihydroxyphenyl)methylene]-N-phenylhydrazine carbothioamsolidide
• CAS No.: 502491-87-4
• Molecular Formula: C₁₄H₁₃N₃O₃S
• Molecular Weight: 303.342
• Mol file: 502491-87-4.mol

Synonyms:2-[(2,3,4-trihydroxyphenyl)methylene]-N-phenylhydrazine carbothioamsolidide

Chemical Property of 2-[(2,3,4-trihydroxyphenyl)methylene]-N-phenylhydrazine carbothioamsolidide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-[(2,3,4-trihydroxyphenyl)methylene]-N-phenylhydrazine carbothioamsolidide

There total 2 articles about 2-[(2,3,4-trihydroxyphenyl)methylene]-N-phenylhydrazine carbothioamsolidide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

2,3,4-trihydroxybenzylaldehyde (2144-08-3) + 4-Phenyl-3-thiosemicarbazide (5351-69-9) → 2-[(2,3,4-trihydroxyphenyl)methylene]-N-phenylhydrazine carbothioamsolidide (502491-87-4)

Guidance literature:

In ethanol; for 4h; Reflux;

DOI:10.1016/j.molstruc.2021.130815

Reference yield:

phenyl isothiocyanate (103-72-0) → 2-[(2,3,4-trihydroxyphenyl)methylene]-N-phenylhydrazine carbothioamsolidide (502491-87-4)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrazine hydrate / methanol / 1 h

2: methanol / 6 h / Reflux

With hydrazine hydrate; In methanol;

DOI:10.1039/d1ob01521d

Reference yield: 71.0%

nickel(II) chloride hexahydrate + 2-[(2,3,4-trihydroxyphenyl)methylene]-N-phenylhydrazine carbothioamsolidide (502491-87-4) + triphenylphosphine (603-35-0) → (2,3,4-trihydroxybenzaldehyde-4-phenyl-3-thiosemicarbazonato)(triphenylphosphine)Ni(II)

Guidance literature:

In ethanol; for 6h; Reflux;

DOI:10.1016/j.molstruc.2021.130815

upstream raw materials:

2,3,4-trihydroxybenzylaldehyde

4-Phenyl-3-thiosemicarbazide

phenyl isothiocyanate

Downstream raw materials:

C₁₉H₁₇N₃O₃S*BrH

C₁₇H₁₅N₃O₃S*ClH