Technology Process of Isopropyl butyl(tert-butyl)borinate
There total 2 articles about Isopropyl butyl(tert-butyl)borinate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
hydrogenchloride;
In
diethyl ether;
byproducts: LiCl, 2-propanol; 1 equiv of tert-BuLi slowly adding to a soln. of the boronic ester at -78°C, stirring for 3 h at the same temp., 1 equiv of anhydrous HCl in Et2O adding, allowing to warm to room temp., stirring for 15 min; the content was detd. by (11)B NMR spectrum;
DOI:10.1021/om00129a019
- Guidance literature:
-
In
diethyl ether;
byproducts: LiCl, 2-propanol; 1 equiv of tert-BuLi slowly adding to a soln. of the boronic ester at -78°C, stirring for 3 h at the same temp., 1 equiv of anhydrous HCl in ether adding, warming to room temp., decanting from the ppt. of LiCl, washing with ether, evavpg.; isolated by fractional distillation, identified by elem. anal., NMR andmass spectra;
DOI:10.1021/om00129a019
