(R)-2,2-dimethyl-1,3-dioxolan-4-ylcarbonyl chloride

Base Information

Chemical Name:(R)-2,2-dimethyl-1,3-dioxolan-4-ylcarbonyl chloride
CAS No.:97673-82-0
Molecular Formula:C₆H₉ClO₃
Molecular Weight:164.589
Hs Code.:
DSSTox Substance ID:DTXSID50438834
Nikkaji Number:J2.486.726I
Wikidata:Q82254667
Mol file:97673-82-0.mol

Synonyms:(4R)-2,2-dimethyl-1,3-dioxolane-4-carbonyl Chloride;97673-82-0;(R)-2,2-dimethyl-1,3-dioxolan-4-ylcarbonyl chloride;SCHEMBL7078356;DTXSID50438834;LFLHAXOMFLJNJK-SCSAIBSYSA-N

Suppliers and Price of (R)-2,2-dimethyl-1,3-dioxolan-4-ylcarbonyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of (R)-2,2-dimethyl-1,3-dioxolan-4-ylcarbonyl chloride

Chemical Property:

Boiling Point:183.9±35.0 °C (760 mmHg)
PSA：35.53000
Density:1.216±0.06 g/cm3 (20 °C, 760 mmHg)
LogP:0.90330
XLogP3:1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:164.0240218
Heavy Atom Count:10
Complexity:155

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(OCC(O1)C(=O)Cl)C
Isomeric SMILES:CC1(OC[C@@H](O1)C(=O)Cl)C

Technology Process of (R)-2,2-dimethyl-1,3-dioxolan-4-ylcarbonyl chloride

There total 6 articles about (R)-2,2-dimethyl-1,3-dioxolan-4-ylcarbonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 14028-61-6,83400-91-3,117205-81-9,130111-05-6
Kaliumsalz der O-Isopropyliden-D-glycerinsaeure

: 73945-73-0,90493-96-2,97673-82-0,116561-26-3
O-Isopropyliden-D-glycerinsaeurechlorid

Guidance literature:: With pyridine; thionyl chloride; N,N-dimethyl-formamide; In diethyl ether; for 2h; Heating;
DOI:10.1007/BF00799972

Reference yield:

: 114746-70-2,62075-55-2
(R)-2,2-dimethyl-[1,3]dioxolane-4-carboxylic acid

: 73945-73-0,90493-96-2,97673-82-0,116561-26-3
(R)-2,3-o-isopropylidene-D-glyceroyl chloride

Guidance literature:: With oxalyl dichloride; In tetrahydrofuran; for 2h; Ambient temperature;
DOI:10.1016/S0040-4039(00)95050-0

Reference yield:

: 15186-48-8
2,3-isopropylidene-glyceraldehyde

: 73945-73-0,90493-96-2,97673-82-0,116561-26-3
(R)-2,3-o-isopropylidene-D-glyceroyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1: KMnO₄, KOH / H₂O / Ambient temperature

2: oxalyl chloride, pyridine / diethyl ether / 1.) ice-cooling, 2 h, 2.) r.t., 20 h

With pyridine; potassium hydroxide; potassium permanganate; oxalyl dichloride; In diethyl ether; water;
DOI:10.1271/bbb1961.44.199