(E)-2-((2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-yl)methyl)-3-((2-nitrophenylsulfonamido)methyl)dec-2-enyl acetate

Base Information

Chemical Name:(E)-2-((2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-yl)methyl)-3-((2-nitrophenylsulfonamido)methyl)dec-2-enyl acetate
CAS No.:1442642-26-3
Molecular Formula:C₂₆H₃₆N₂O₁₀S
Molecular Weight:568.645
Hs Code.:

Synonyms:(E)-2-((2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-yl)methyl)-3-((2-nitrophenylsulfonamido)methyl)dec-2-enyl acetate

Suppliers and Price of (E)-2-((2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-yl)methyl)-3-((2-nitrophenylsulfonamido)methyl)dec-2-enyl acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (E)-2-((2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-yl)methyl)-3-((2-nitrophenylsulfonamido)methyl)dec-2-enyl acetate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (E)-2-((2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-yl)methyl)-3-((2-nitrophenylsulfonamido)methyl)dec-2-enyl acetate

There total 4 articles about (E)-2-((2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-yl)methyl)-3-((2-nitrophenylsulfonamido)methyl)dec-2-enyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 2033-24-1
cycl-isopropylidene malonate

: 1442642-69-4
(E)-2-(hydroxymethyl)-3-((2-nitrophenylsulfonamido)methyl)dec-2-enyl acetate

: 1442642-26-3
(E)-2-((2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-yl)methyl)-3-((2-nitrophenylsulfonamido)methyl)dec-2-enyl acetate

Guidance literature:: With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; at 20 ℃; for 1h;
DOI:10.1002/adsc.201200242

Reference yield:

: C₂₁H₃₂N₂O₆S

: 1442642-26-3
(E)-2-((2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-yl)methyl)-3-((2-nitrophenylsulfonamido)methyl)dec-2-enyl acetate

Guidance literature:: Multi-step reaction with 3 steps

1: toluene-4-sulfonic acid / methanol / 24 h

2: 2,4,6-trimethyl-pyridine; (2S,5S)-2,5-bis[[(2S)-3-(2-naphthylmethyl)-1-(octyloxy)-1-oxopropan-2-ylamino]carbonyl]-1-(pyridin-4-yl)pyrrolidine / chloroform / 24 h / -60 °C

3: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 1 h / 20 °C

With 2,4,6-trimethyl-pyridine; (2S,5S)-2,5-bis[[(2S)-3-(2-naphthylmethyl)-1-(octyloxy)-1-oxopropan-2-ylamino]carbonyl]-1-(pyridin-4-yl)pyrrolidine; di-isopropyl azodicarboxylate; toluene-4-sulfonic acid; triphenylphosphine; In tetrahydrofuran; methanol; chloroform; 3: |Mitsunobu Displacement;
DOI:10.1002/adsc.201200242

Reference yield:

: 1442642-82-1
N-(2-(1,3-dihydroxypropan-2-ylidene)nonyl)-2-nitrobenzenesulfonamide

: 1442642-26-3
(E)-2-((2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-yl)methyl)-3-((2-nitrophenylsulfonamido)methyl)dec-2-enyl acetate

Guidance literature:: Multi-step reaction with 2 steps

1: 2,4,6-trimethyl-pyridine; (2S,5S)-2,5-bis[[(2S)-3-(2-naphthylmethyl)-1-(octyloxy)-1-oxopropan-2-ylamino]carbonyl]-1-(pyridin-4-yl)pyrrolidine / chloroform / 24 h / -60 °C

2: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 1 h / 20 °C

With 2,4,6-trimethyl-pyridine; (2S,5S)-2,5-bis[[(2S)-3-(2-naphthylmethyl)-1-(octyloxy)-1-oxopropan-2-ylamino]carbonyl]-1-(pyridin-4-yl)pyrrolidine; di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; chloroform; 2: |Mitsunobu Displacement;
DOI:10.1002/adsc.201200242