Methyl bicyclo[3.1.0]hexane-2-carboxylate

Base Information

• Chemical Name: Methyl bicyclo[3.1.0]hexane-2-carboxylate
• CAS No.: 92984-39-9
• Molecular Formula: C₈H₁₂O₂
• Molecular Weight: 140.182
• DSSTox Substance ID: DTXSID10507292
• Mol file: 92984-39-9.mol

Synonyms:92984-39-9;Methyl bicyclo[3.1.0]hexane-2-carboxylate;DTXSID10507292

Chemical Property of Methyl bicyclo[3.1.0]hexane-2-carboxylate

Chemical Property:

• PSA: 26.30000
• LogP: 1.20550
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 140.083729621
• Heavy Atom Count: 10
• Complexity: 165

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC(=O)C1CCC2C1C2

Technology Process of Methyl bicyclo[3.1.0]hexane-2-carboxylate

There total 1 articles about Methyl bicyclo[3.1.0]hexane-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ trans-2-Carbomethoxybicyclo<3.1.0>hexan (15733-76-3,15733-77-4,92984-39-9)

Guidance literature:

aus trans-Bicyclo<3.1.0>hexan-2-ol;

DOI:10.1021/jo01258a086

Reference yield:

(1R,2S,5S)-Bicyclo[3.1.0]hexane-2-carboxylic acid methyl ester (15733-76-3,15733-77-4,92984-39-9) → chloromethyl-2-bicyclo<3.1.0>hexane-cis (78002-54-7,78002-55-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 62 percent / LiAlH₄ / diethyl ether / 3 h / Heating

2: 35 percent / SOCl₂, pyridine / diethyl ether / 2 h / Heating

With pyridine; lithium aluminium tetrahydride; thionyl chloride; In diethyl ether;

Downstream raw materials:

chloromethyl-2-bicyclo<3.1.0>hexane-cis