10-(2-{[tert-butyl(diphenyl)silyl]oxy}-4-[2-(4-methoxyphenyl)-2H-tetrazol-5-yl]butyl)-N-(2-morpholin-4-ylethyl)-10H-phenothiazin-2-amine

Base Information

Chemical Name:10-(2-{[tert-butyl(diphenyl)silyl]oxy}-4-[2-(4-methoxyphenyl)-2H-tetrazol-5-yl]butyl)-N-(2-morpholin-4-ylethyl)-10H-phenothiazin-2-amine
CAS No.:1442371-86-9
Molecular Formula:C₄₆H₅₃N₇O₃SSi
Molecular Weight:812.123
Hs Code.:

Synonyms:10-(2-{[tert-butyl(diphenyl)silyl]oxy}-4-[2-(4-methoxyphenyl)-2H-tetrazol-5-yl]butyl)-N-(2-morpholin-4-ylethyl)-10H-phenothiazin-2-amine

Suppliers and Price of 10-(2-{[tert-butyl(diphenyl)silyl]oxy}-4-[2-(4-methoxyphenyl)-2H-tetrazol-5-yl]butyl)-N-(2-morpholin-4-ylethyl)-10H-phenothiazin-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 10-(2-{[tert-butyl(diphenyl)silyl]oxy}-4-[2-(4-methoxyphenyl)-2H-tetrazol-5-yl]butyl)-N-(2-morpholin-4-ylethyl)-10H-phenothiazin-2-amine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 10-(2-{[tert-butyl(diphenyl)silyl]oxy}-4-[2-(4-methoxyphenyl)-2H-tetrazol-5-yl]butyl)-N-(2-morpholin-4-ylethyl)-10H-phenothiazin-2-amine

There total 3 articles about 10-(2-{[tert-butyl(diphenyl)silyl]oxy}-4-[2-(4-methoxyphenyl)-2H-tetrazol-5-yl]butyl)-N-(2-morpholin-4-ylethyl)-10H-phenothiazin-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2038-03-1
4-(2-AMINOETHYL)MORPHOLINE

: 1442371-84-7
10-(2-{[tert-butyl(diphenyl)silyl]oxy}-4-[2-(4-methoxyphenyl)-2H-tetrazol-5-yl]butyl)-2-chloro-10H-phenothiazine

: 1442371-86-9
10-(2-{[tert-butyl(diphenyl)silyl]oxy}-4-[2-(4-methoxyphenyl)-2H-tetrazol-5-yl]butyl)-N-(2-morpholin-4-ylethyl)-10H-phenothiazin-2-amine

Guidance literature:: With XPhos; at 100 - 110 ℃; for 31h; Inert atmosphere; Alkaline conditions;
DOI:10.1016/j.bmc.2013.04.034

Reference yield:

: 1387627-09-9
1-(2-chloro-10H-phenothiazin-10-yl)-4-(2-(4-methoxyphenyl)-2H-tetrazol-5-yl)butan-2-ol

: 1442371-86-9
10-(2-{[tert-butyl(diphenyl)silyl]oxy}-4-[2-(4-methoxyphenyl)-2H-tetrazol-5-yl]butyl)-N-(2-morpholin-4-ylethyl)-10H-phenothiazin-2-amine

Guidance literature:: Multi-step reaction with 2 steps

1: 1H-imidazole / dichloromethane / 96 h / 0 - 20 °C / Inert atmosphere

2: XPhos / 31 h / 100 - 110 °C / Inert atmosphere; Alkaline conditions

With 1H-imidazole; XPhos; In dichloromethane; 2: |Buchwald-Hartwig Coupling;
DOI:10.1016/j.bmc.2013.04.034

Reference yield:

: 58479-61-1
tert-butylchlorodiphenylsilane

: 1442371-86-9
10-(2-{[tert-butyl(diphenyl)silyl]oxy}-4-[2-(4-methoxyphenyl)-2H-tetrazol-5-yl]butyl)-N-(2-morpholin-4-ylethyl)-10H-phenothiazin-2-amine

Guidance literature:: Multi-step reaction with 2 steps

1: 1H-imidazole / dichloromethane / 96 h / 0 - 20 °C / Inert atmosphere

2: XPhos / 31 h / 100 - 110 °C / Inert atmosphere; Alkaline conditions

With 1H-imidazole; XPhos; In dichloromethane; 2: |Buchwald-Hartwig Coupling;
DOI:10.1016/j.bmc.2013.04.034