3-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-2-methyl-2-(1-prop-2-enyl)propanal

Base Information

• Chemical Name: 3-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-2-methyl-2-(1-prop-2-enyl)propanal
• CAS No.: 938174-26-6
• Molecular Formula: C₂₁H₃₂O₂
• Molecular Weight: 316.484
• Mol file: 938174-26-6.mol

Synonyms:3-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-2-methyl-2-(1-prop-2-enyl)propanal

Chemical Property of 3-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-2-methyl-2-(1-prop-2-enyl)propanal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-2-methyl-2-(1-prop-2-enyl)propanal

There total 2 articles about 3-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-2-methyl-2-(1-prop-2-enyl)propanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

2,6-di-tert-butyl-4-methoxymethylene-phenol (87-97-8) + propionaldehyde (123-38-6) → 3-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-2-methyl-2-(1-prop-2-enyl)propanal (938174-26-6)

Guidance literature:

With potassium hydroxide; In methanol; at 60 ℃; for 3h;

DOI:10.1071/CH06164

Reference yield:

2,6-di-tert-butylphenol (128-39-2) → 3-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-2-methyl-2-(1-prop-2-enyl)propanal (938174-26-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / KOH

2: 45 percent / potassium hydroxide / methanol / 3 h / 60 °C

With potassium hydroxide; In methanol;

DOI:10.1071/CH06164

Reference yield: 74.0%

3-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-2-methyl-2-(1-prop-2-enyl)propanal (938174-26-6) → 3-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-2-methyl-2-(1-prop-2-enyl)propanol

Guidance literature:

With sodium tetrahydroborate; In ethanol; Heating;

DOI:10.1071/CH06164

upstream raw materials:

2,6-di-tert-butyl-4-methoxymethylene-phenol

propionaldehyde

2,6-di-tert-butylphenol