(4S,4'R,6S)-4,6-diethyl-4-(4-ethyl-2-methylocta-1,5-dienyl)-2-phenyl-6-vinyl-1,3-dioxane

Base Information

Chemical Name:(4S,4'R,6S)-4,6-diethyl-4-(4-ethyl-2-methylocta-1,5-dienyl)-2-phenyl-6-vinyl-1,3-dioxane
CAS No.:916501-87-6
Molecular Formula:C₂₇H₄₀O₂
Molecular Weight:396.613
Hs Code.:

Synonyms:(4S,4'R,6S)-4,6-diethyl-4-(4-ethyl-2-methylocta-1,5-dienyl)-2-phenyl-6-vinyl-1,3-dioxane

Suppliers and Price of (4S,4'R,6S)-4,6-diethyl-4-(4-ethyl-2-methylocta-1,5-dienyl)-2-phenyl-6-vinyl-1,3-dioxane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (4S,4'R,6S)-4,6-diethyl-4-(4-ethyl-2-methylocta-1,5-dienyl)-2-phenyl-6-vinyl-1,3-dioxane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (4S,4'R,6S)-4,6-diethyl-4-(4-ethyl-2-methylocta-1,5-dienyl)-2-phenyl-6-vinyl-1,3-dioxane

There total 15 articles about (4S,4'R,6S)-4,6-diethyl-4-(4-ethyl-2-methylocta-1,5-dienyl)-2-phenyl-6-vinyl-1,3-dioxane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 916501-84-3
(4S,6S)-4,6-diethyl-2-phenyl-6-vinyl-1,3-dioxane-4-carbaldehyde

: 916501-87-6
(4S,4'R,6S)-4,6-diethyl-4-(4-ethyl-2-methylocta-1,5-dienyl)-2-phenyl-6-vinyl-1,3-dioxane

Guidance literature:: Multi-step reaction with 4 steps

1.1: 95 percent / t-BuOK / tetrahydrofuran / 18 h / -55 - 23 °C

2.1: n-BuLi / tetrahydrofuran; hexane / 0.5 h / -78 °C

2.2: 95 percent / tetrahydrofuran; hexane / 1 h / -78 °C

3.1: tricyclohexylphosphine; tributyltin hydride / Pd(OAc)2 / hexane / 15 h / -35 °C

3.2: 29 percent / N-iodosuccinimide / tetrahydrofuran / 2 h / 0 °C

4.1: t-BuLi; 9-methoxy-9-borabicyclo[3.3.1]nonane / diethyl ether; pentane; tetrahydrofuran / -78 - 23 °C

4.2: 81 percent / aq. K₃PO₄; DMF / PdCl₂(dppf)*CHCl₃ / diethyl ether; pentane; tetrahydrofuran / 16 h / 23 °C

With n-butyllithium; potassium tert-butylate; tert.-butyl lithium; tri-n-butyl-tin hydride; 9-methoxy-9-BBN; tricyclohexylphosphine; palladium diacetate; In tetrahydrofuran; diethyl ether; hexane; pentane;
DOI:10.1021/ol0618656

Reference yield:

: 916502-00-6
(4S,6S)-(4,6-diethyl-2-phenyl-6-vinyl-1,3-dioxan-4-yl)methanol

: 916501-87-6
(4S,4'R,6S)-4,6-diethyl-4-(4-ethyl-2-methylocta-1,5-dienyl)-2-phenyl-6-vinyl-1,3-dioxane

Guidance literature:: Multi-step reaction with 5 steps

1.1: 83 percent / 4 Angstroem molecular sieves; pyridinium chlorochromate; AcOH / CH₂Cl₂ / 14 h / 0 - 23 °C

2.1: 95 percent / t-BuOK / tetrahydrofuran / 18 h / -55 - 23 °C

3.1: n-BuLi / tetrahydrofuran; hexane / 0.5 h / -78 °C

3.2: 95 percent / tetrahydrofuran; hexane / 1 h / -78 °C

4.1: tricyclohexylphosphine; tributyltin hydride / Pd(OAc)2 / hexane / 15 h / -35 °C

4.2: 29 percent / N-iodosuccinimide / tetrahydrofuran / 2 h / 0 °C

5.1: t-BuLi; 9-methoxy-9-borabicyclo[3.3.1]nonane / diethyl ether; pentane; tetrahydrofuran / -78 - 23 °C

5.2: 81 percent / aq. K₃PO₄; DMF / PdCl₂(dppf)*CHCl₃ / diethyl ether; pentane; tetrahydrofuran / 16 h / 23 °C

With n-butyllithium; 4 A molecular sieve; potassium tert-butylate; tert.-butyl lithium; tri-n-butyl-tin hydride; acetic acid; 9-methoxy-9-BBN; pyridinium chlorochromate; tricyclohexylphosphine; palladium diacetate; In tetrahydrofuran; diethyl ether; hexane; dichloromethane; pentane;
DOI:10.1021/ol0618656

Reference yield:

: 916501-85-4
(4S,6S)-4,6-diethyl-2-phenyl-4-prop-1-ynyl-6-vinyl-1,3-dioxane

: 916501-87-6
(4S,4'R,6S)-4,6-diethyl-4-(4-ethyl-2-methylocta-1,5-dienyl)-2-phenyl-6-vinyl-1,3-dioxane

Guidance literature:: Multi-step reaction with 2 steps

1.1: tricyclohexylphosphine; tributyltin hydride / Pd(OAc)2 / hexane / 15 h / -35 °C

1.2: 29 percent / N-iodosuccinimide / tetrahydrofuran / 2 h / 0 °C

2.1: t-BuLi; 9-methoxy-9-borabicyclo[3.3.1]nonane / diethyl ether; pentane; tetrahydrofuran / -78 - 23 °C

2.2: 81 percent / aq. K₃PO₄; DMF / PdCl₂(dppf)*CHCl₃ / diethyl ether; pentane; tetrahydrofuran / 16 h / 23 °C

With tert.-butyl lithium; tri-n-butyl-tin hydride; 9-methoxy-9-BBN; tricyclohexylphosphine; palladium diacetate; In tetrahydrofuran; diethyl ether; hexane; pentane;
DOI:10.1021/ol0618656