5'-O-(N-(3-((R)-2,4-dihydroxy-3,3-dimethylbutanamido)propanoyl)sulfamoyl)-2',3'-O,N⁽⁴⁾-tribenzoylcytidine

Base Information

• Chemical Name: 5'-O-(N-(3-((R)-2,4-dihydroxy-3,3-dimethylbutanamido)propanoyl)sulfamoyl)-2',3'-O,N⁽⁴⁾-tribenzoylcytidine
• CAS No.: 1196055-85-2
• Molecular Formula: C₃₉H₄₁N₅O₁₄S
• Molecular Weight: 835.846
• Mol file: 1196055-85-2.mol

Synonyms:5'-O-(N-(3-((R)-2,4-dihydroxy-3,3-dimethylbutanamido)propanoyl)sulfamoyl)-2',3'-O,N⁽⁴⁾-tribenzoylcytidine

Chemical Property of 5'-O-(N-(3-((R)-2,4-dihydroxy-3,3-dimethylbutanamido)propanoyl)sulfamoyl)-2',3'-O,N⁽⁴⁾-tribenzoylcytidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5'-O-(N-(3-((R)-2,4-dihydroxy-3,3-dimethylbutanamido)propanoyl)sulfamoyl)-2',3'-O,N⁽⁴⁾-tribenzoylcytidine

There total 1 articles about 5'-O-(N-(3-((R)-2,4-dihydroxy-3,3-dimethylbutanamido)propanoyl)sulfamoyl)-2',3'-O,N⁽⁴⁾-tribenzoylcytidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

5'-O-(N-(3-((4R)-2-(4-methoxyphenyl)-5,5-dimethyl-1,3-dioxane-4-carboxamido)propanoyl)sulfamoyl)-2',3'-O,N(4)-tribenzoylcytidine (1196055-81-8) → 5'-O-(N-(3-((R)-2,4-dihydroxy-3,3-dimethylbutanamido)propanoyl)sulfamoyl)-2',3'-O,N(4)-tribenzoylcytidine (1196055-85-2)

Guidance literature:

With water; acetic acid; at 20 ℃; for 12h;

DOI:10.1021/ja906537f

Reference yield:

5'-O-(N-(3-((R)-2,4-dihydroxy-3,3-dimethylbutanamido)propanoyl)sulfamoyl)-2',3'-O,N(4)-tribenzoylcytidine (1196055-85-2) + bis(2-cyanoethyl) diisopropylamidophosphite (102690-88-0) → C42H43N6O15PS

Guidance literature:

With 5-(ethylthio)-1H-tetrazole; In acetonitrile; at 20 ℃; for 4h; Molecular sieve;

DOI:10.1021/ja906537f

Reference yield:

5'-O-(N-(3-((R)-2,4-dihydroxy-3,3-dimethylbutanamido)propanoyl)sulfamoyl)-2',3'-O,N(4)-tribenzoylcytidine (1196055-85-2) + bis(2-cyanoethyl) diisopropylamidophosphite (102690-88-0) → C45H48N7O16PS

Guidance literature:

With pyridine; pyridine hydrochloride; at -20 ℃; Molecular sieve;

DOI:10.1021/ja906537f

upstream raw materials:

5'-O-(N-(3-((4R)-2-(4-methoxyphenyl)-5,5-dimethyl-1,3-dioxane-4-carboxamido)propanoyl)sulfamoyl)-2',3'-O,N⁽⁴⁾-tribenzoylcytidine