2-(2-ethenylphenyl)-4,4-dimethoxy-3-(2-methyl-1-propenyl)cyclobutenone

Base Information

• Chemical Name: 2-(2-ethenylphenyl)-4,4-dimethoxy-3-(2-methyl-1-propenyl)cyclobutenone
• CAS No.: 205124-18-1
• Molecular Formula: C₁₈H₂₀O₃
• Molecular Weight: 284.355
• Mol file: 205124-18-1.mol

Synonyms:2-(2-ethenylphenyl)-4,4-dimethoxy-3-(2-methyl-1-propenyl)cyclobutenone

Chemical Property of 2-(2-ethenylphenyl)-4,4-dimethoxy-3-(2-methyl-1-propenyl)cyclobutenone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(2-ethenylphenyl)-4,4-dimethoxy-3-(2-methyl-1-propenyl)cyclobutenone

There total 4 articles about 2-(2-ethenylphenyl)-4,4-dimethoxy-3-(2-methyl-1-propenyl)cyclobutenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

2-methylprop-1-enyllithium (29917-94-0) + 2-(2-vinylphenyl)-3,4,4-trimethoxy-2-cyclobutene-1-one (205124-30-7) → 2-(2-ethenylphenyl)-4,4-dimethoxy-3-(2-methyl-1-propenyl)cyclobutenone (205124-18-1)

Guidance literature:

In tetrahydrofuran; at -78 ℃;

DOI:10.1021/ja980039s

Reference yield:

1-lithio-2-vinylbenzene (142011-02-7) → 2-(2-ethenylphenyl)-4,4-dimethoxy-3-(2-methyl-1-propenyl)cyclobutenone (205124-18-1)

Guidance literature:

Multi-step reaction with 3 steps

1: tetrahydrofuran / -78 °C

2: TFAA

3: 88 percent / tetrahydrofuran / -78 °C

With trifluoroacetic anhydride; In tetrahydrofuran;

DOI:10.1021/ja980039s

Reference yield:

3,4-dimethoxy-3-cyclobutene-1,2-dione (5222-73-1) → 2-(2-ethenylphenyl)-4,4-dimethoxy-3-(2-methyl-1-propenyl)cyclobutenone (205124-18-1)

Guidance literature:

Multi-step reaction with 3 steps

1: tetrahydrofuran / -78 °C

2: TFAA

3: 88 percent / tetrahydrofuran / -78 °C

With trifluoroacetic anhydride; In tetrahydrofuran;

DOI:10.1021/ja980039s

upstream raw materials:

2-methylprop-1-enyllithium

2-(2-vinylphenyl)-3,4,4-trimethoxy-2-cyclobutene-1-one

1-lithio-2-vinylbenzene

3,4-dimethoxy-3-cyclobutene-1,2-dione

Downstream raw materials:

benz[a]anthracene-7,12-dione