allyl [2-[4-[bis(2-chloroethyl)amino]benzyl]-4,7-dioxo-4,7-dihydro-2H-isoindol-5-yl]carbamate

Base Information

Chemical Name:allyl [2-[4-[bis(2-chloroethyl)amino]benzyl]-4,7-dioxo-4,7-dihydro-2H-isoindol-5-yl]carbamate
CAS No.:959843-08-4
Molecular Formula:C₂₃H₂₃Cl₂N₃O₄
Molecular Weight:476.359
Hs Code.:

Synonyms:allyl [2-[4-[bis(2-chloroethyl)amino]benzyl]-4,7-dioxo-4,7-dihydro-2H-isoindol-5-yl]carbamate

Suppliers and Price of allyl [2-[4-[bis(2-chloroethyl)amino]benzyl]-4,7-dioxo-4,7-dihydro-2H-isoindol-5-yl]carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of allyl [2-[4-[bis(2-chloroethyl)amino]benzyl]-4,7-dioxo-4,7-dihydro-2H-isoindol-5-yl]carbamate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of allyl [2-[4-[bis(2-chloroethyl)amino]benzyl]-4,7-dioxo-4,7-dihydro-2H-isoindol-5-yl]carbamate

There total 5 articles about allyl [2-[4-[bis(2-chloroethyl)amino]benzyl]-4,7-dioxo-4,7-dihydro-2H-isoindol-5-yl]carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: allyl [2-[4-[bis(2-hydroxyethyl)amino]benzyl]-4,7-dioxo-4,7-dihydro-2H-isoindol-5-yl]carbamate

: 959843-08-4
allyl [2-[4-[bis(2-chloroethyl)amino]benzyl]-4,7-dioxo-4,7-dihydro-2H-isoindol-5-yl]carbamate

Guidance literature:: With triethylamine; In dichloromethane; for 0.25h;
DOI:10.1007/s00706-007-0604-7

Reference yield:

: allyl [2-[4-[(tert-butoxycarbonyl)amino]benzyl]-4,7-dioxo-4,7-dihydro-2H-isoindol-5-yl]carbamate

: 959843-08-4
allyl [2-[4-[bis(2-chloroethyl)amino]benzyl]-4,7-dioxo-4,7-dihydro-2H-isoindol-5-yl]carbamate

Guidance literature:: Multi-step reaction with 3 steps

1: 65 percent / trifluoroacetic acid / CH₂Cl₂ / 2 h / 20 °C

2: 77 percent / ethanol; H₂O / 39 h / Heating

3: 85 percent / Et₃N; methanesulfonic acid chloride / CH₂Cl₂ / 0.25 h

With triethylamine; trifluoroacetic acid; In ethanol; dichloromethane; water;
DOI:10.1007/s00706-007-0604-7

Reference yield:

: allyl [2-(4-aminobenzyl)-4,7-dioxo-4,7-dihydro-2H-isoindol-5-yl]carbamate

: 959843-08-4
allyl [2-[4-[bis(2-chloroethyl)amino]benzyl]-4,7-dioxo-4,7-dihydro-2H-isoindol-5-yl]carbamate

Guidance literature:: Multi-step reaction with 2 steps

1: 77 percent / ethanol; H₂O / 39 h / Heating

2: 85 percent / Et₃N; methanesulfonic acid chloride / CH₂Cl₂ / 0.25 h

With triethylamine; In ethanol; dichloromethane; water;
DOI:10.1007/s00706-007-0604-7