7-{(1R,2R)-2-[3-(4-Amino-phenoxy)-propylamino]-cyclopentyl}-heptanoic acid ethyl ester

Base Information

Chemical Name:7-{(1R,2R)-2-[3-(4-Amino-phenoxy)-propylamino]-cyclopentyl}-heptanoic acid ethyl ester
CAS No.:107556-00-3
Molecular Formula:C₂₃H₃₈N₂O₃
Molecular Weight:390.566
Hs Code.:

Synonyms:7-{(1R,2R)-2-[3-(4-Amino-phenoxy)-propylamino]-cyclopentyl}-heptanoic acid ethyl ester

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Chemical Property of 7-{(1R,2R)-2-[3-(4-Amino-phenoxy)-propylamino]-cyclopentyl}-heptanoic acid ethyl ester

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Technology Process of 7-{(1R,2R)-2-[3-(4-Amino-phenoxy)-propylamino]-cyclopentyl}-heptanoic acid ethyl ester

There total 3 articles about 7-{(1R,2R)-2-[3-(4-Amino-phenoxy)-propylamino]-cyclopentyl}-heptanoic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 107539-67-3,107539-68-4
ethyl trans-(p-nitrophenoxy)prostanoate

: 107556-00-3
7-{(1R,2R)-2-[3-(4-Amino-phenoxy)-propylamino]-cyclopentyl}-heptanoic acid ethyl ester

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; for 10h; under 1810.02 Torr;
DOI:10.1021/jm00388a029

Reference yield:

: 40687-10-3
2-(6-ethoxycarbonylhexyl)cyclopentan-1-one

: 107556-00-3
7-{(1R,2R)-2-[3-(4-Amino-phenoxy)-propylamino]-cyclopentyl}-heptanoic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) 4A molecular sieves, 2.) NaBH₄ / 1.) ethanol, RT, 48 h, 2.) ethanol, 30 min

2: 89 percent / H₂ / 10percent Pd/C / ethanol / 10 h / 1810.02 Torr

With sodium tetrahydroborate; 4 A molecular sieve; hydrogen; palladium on activated charcoal; In ethanol;
DOI:10.1021/jm00388a029

Reference yield:

: 100841-04-1
3-(4-nitrophenoxy)propan-1-amine

: 107556-00-3
7-{(1R,2R)-2-[3-(4-Amino-phenoxy)-propylamino]-cyclopentyl}-heptanoic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) 4A molecular sieves, 2.) NaBH₄ / 1.) ethanol, RT, 48 h, 2.) ethanol, 30 min

2: 89 percent / H₂ / 10percent Pd/C / ethanol / 10 h / 1810.02 Torr

With sodium tetrahydroborate; 4 A molecular sieve; hydrogen; palladium on activated charcoal; In ethanol;
DOI:10.1021/jm00388a029