2-HYDROXY-4-METHOXY-BETA-NITROSTYRENE

Base Information

• Chemical Name: 2-HYDROXY-4-METHOXY-BETA-NITROSTYRENE
• CAS No.: 96853-34-8
• Molecular Formula: C9H9 N O4
• Molecular Weight: 195.175
• Hs Code.: 2909500000
• Mol file: 96853-34-8.mol

Synonyms:2-HYDROXY-4-METHOXY-BETA-NITROSTYRENE

Chemical Property of 2-HYDROXY-4-METHOXY-BETA-NITROSTYRENE

Chemical Property:

• PSA: 75.28000
• LogP: 2.17140

Purity/Quality:

97% ^*data from raw suppliers

2-HYDROXY-4-METHOXY-BETA-NITROSTYRENE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-HYDROXY-4-METHOXY-BETA-NITROSTYRENE

There total 2 articles about 2-HYDROXY-4-METHOXY-BETA-NITROSTYRENE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

2-Hydroxy-4-methoxybenzaldehyde (673-22-3) + nitromethane (75-52-5) → (E)-5-methoxy-2-(2-nitrovinyl)phenol (96853-34-8)

Guidance literature:

With ammonium acetate; for 12h; Reflux; Inert atmosphere;

DOI:10.1021/acs.joc.7b02178

Reference yield: 35.0%

2-Hydroxy-4-methoxybenzaldehyde (673-22-3) + nitromethane (75-52-5) → 5-methoxy-2-(2-nitro-vinyl)-phenol (96853-34-8)

Guidance literature:

With ammonium acetate; acetic acid; for 0.75h; Reflux;

DOI:10.1039/c0ob00189a

Reference yield: 90.0%

5-methoxy-2-(2-nitro-vinyl)-phenol (96853-34-8) → C9H9N3O2

Guidance literature:

With sodium azide; bismuth tungstate; In water; at 80 ℃; for 3h; regioselective reaction;

DOI:10.1039/c5ra09544a

upstream raw materials:

2-Hydroxy-4-methoxybenzaldehyde

nitromethane

Downstream raw materials:

(R)-7-methoxy-4-(nitromethyl)-2-phenyl-4H-chromene-3-carbaldehyde

Nitro-2 methoxy-6 benzofuranne

5-Methoxy-2-(2-nitro-ethyl)-phenol

(3aS,9R,9aS)-ethyl 3a-hydroxy-6-methoxy-9-(nitromethyl)-1,2,3,3a,9,9a-hexahydrocyclopenta[b]chromene-9acarboxylate