6-phenyl-7-(4-{[4-(5-pyridin-2-yl-1,2,4-triazol-3-yl)piperidin-1-yl]methyl}phenyl)-3-[(trimethylsilyl)ethynyl]imidazo[1,2-a]pyrimidine

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Chemical Name:6-phenyl-7-(4-{[4-(5-pyridin-2-yl-1,2,4-triazol-3-yl)piperidin-1-yl]methyl}phenyl)-3-[(trimethylsilyl)ethynyl]imidazo[1,2-a]pyrimidine
CAS No.:1116116-63-2
Molecular Formula:C₃₆H₃₆N₈Si
Molecular Weight:608.821
Hs Code.:

Synonyms:6-phenyl-7-(4-{[4-(5-pyridin-2-yl-1,2,4-triazol-3-yl)piperidin-1-yl]methyl}phenyl)-3-[(trimethylsilyl)ethynyl]imidazo[1,2-a]pyrimidine

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Chemical Property of 6-phenyl-7-(4-{[4-(5-pyridin-2-yl-1,2,4-triazol-3-yl)piperidin-1-yl]methyl}phenyl)-3-[(trimethylsilyl)ethynyl]imidazo[1,2-a]pyrimidine

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Technology Process of 6-phenyl-7-(4-{[4-(5-pyridin-2-yl-1,2,4-triazol-3-yl)piperidin-1-yl]methyl}phenyl)-3-[(trimethylsilyl)ethynyl]imidazo[1,2-a]pyrimidine

There total 2 articles about 6-phenyl-7-(4-{[4-(5-pyridin-2-yl-1,2,4-triazol-3-yl)piperidin-1-yl]methyl}phenyl)-3-[(trimethylsilyl)ethynyl]imidazo[1,2-a]pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 868280-68-6
2-(5-piperidin-4-yl-1H-[1,2,4]triazol-3-yl)-pyridine dihydrochloride

: 1116116-62-1
4-{6-phenyl-3-[(trimethylsilyl)ethynyl]imidazo[1,2-a]pyrimidin-7-yl}benzaldehyde

: 1116116-61-0
3-ethynyl-6-phenyl-7-(4-{[4-(5-pyridin-2-yl-1,2,4-triazol-3-yl)piperidin-1-yl]methyl}phenyl)imidazo[1,2-a]pyrimidine

: 1116116-63-2
6-phenyl-7-(4-{[4-(5-pyridin-2-yl-1,2,4-triazol-3-yl)piperidin-1-yl]methyl}phenyl)-3-[(trimethylsilyl)ethynyl]imidazo[1,2-a]pyrimidine

Guidance literature:: With sodium tris(acetoxy)borohydride; acetic acid; triethylamine; In methanol; N,N-dimethyl-formamide; at 20 - 25 ℃; for 22h;

Reference yield:

: 2-(3-piperidin-4-yl-1H-1,2,4-triazol-5-yl)pyridine dihydrochloride

: 1116116-62-1
4-{6-phenyl-3-[(trimethylsilyl)ethynyl]imidazo[1,2-a]pyrimidin-7-yl}benzaldehyde

: 1116116-61-0
3-ethynyl-6-phenyl-7-(4-{[4-(5-pyridin-2-yl-1,2,4-triazol-3-yl)piperidin-1-yl]methyl}phenyl)imidazo[1,2-a]pyrimidine

: 1116116-63-2
6-phenyl-7-(4-{[4-(5-pyridin-2-yl-1,2,4-triazol-3-yl)piperidin-1-yl]methyl}phenyl)-3-[(trimethylsilyl)ethynyl]imidazo[1,2-a]pyrimidine

Guidance literature:: With sodium triacetoxyborohydride; acetic acid; triethylamine; In methanol; N,N-dimethyl-formamide; at 20 ℃; for 22h; Product distribution / selectivity;