(Z)-1-[4-(2-fluoroethoxy)phenyl]-1-phenyl-2-(4-methylsulfonylphenyl)hex-1-ene

Base Information

• Chemical Name: (Z)-1-[4-(2-fluoroethoxy)phenyl]-1-phenyl-2-(4-methylsulfonylphenyl)hex-1-ene
• CAS No.: 1247065-47-9
• Molecular Formula: C₂₇H₂₉FO₃S
• Molecular Weight: 452.59

Synonyms:(Z)-1-[4-(2-fluoroethoxy)phenyl]-1-phenyl-2-(4-methylsulfonylphenyl)hex-1-ene

Chemical Property of (Z)-1-[4-(2-fluoroethoxy)phenyl]-1-phenyl-2-(4-methylsulfonylphenyl)hex-1-ene

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Technology Process of (Z)-1-[4-(2-fluoroethoxy)phenyl]-1-phenyl-2-(4-methylsulfonylphenyl)hex-1-ene

There total 1 articles about (Z)-1-[4-(2-fluoroethoxy)phenyl]-1-phenyl-2-(4-methylsulfonylphenyl)hex-1-ene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

2-fluoroethyl tosylate (383-50-6) + (Z)-1-(4-hydroxyphenyl)-1-phenyl-2-(4-methylsulfonylphenyl)hex-1-ene → (Z)-1-[4-(2-fluoroethoxy)phenyl]-1-phenyl-2-(4-methylsulfonylphenyl)hex-1-ene (1247065-47-9)

Guidance literature:

(Z)-1-(4-hydroxyphenyl)-1-phenyl-2-(4-methylsulfonylphenyl)hex-1-ene; With potassium carbonate; [2.2.2]cryptande; In acetonitrile; at 50 ℃; for 0.25h;

2-fluoroethyl tosylate; In acetonitrile; for 0.166667h; Reflux;

DOI:10.1016/j.bmcl.2010.06.155

upstream raw materials:

2-fluoroethyl tosylate

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