6-[[2-(4-chlorophenyl)-2-oxoethyl]thio]-1,5-dihydro-1-phenyl-4H-pyrazolo[3,4-d]pyrimidin-4-one

Base Information

• Chemical Name: 6-[[2-(4-chlorophenyl)-2-oxoethyl]thio]-1,5-dihydro-1-phenyl-4H-pyrazolo[3,4-d]pyrimidin-4-one
• CAS No.: 478247-52-8
• Molecular Formula: C₁₉H₁₃ClN₄O₂S
• Molecular Weight: 396.857
• Mol file: 478247-52-8.mol

Synonyms:6-[[2-(4-chlorophenyl)-2-oxoethyl]thio]-1,5-dihydro-1-phenyl-4H-pyrazolo[3,4-d]pyrimidin-4-one

Chemical Property of 6-[[2-(4-chlorophenyl)-2-oxoethyl]thio]-1,5-dihydro-1-phenyl-4H-pyrazolo[3,4-d]pyrimidin-4-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6-[[2-(4-chlorophenyl)-2-oxoethyl]thio]-1,5-dihydro-1-phenyl-4H-pyrazolo[3,4-d]pyrimidin-4-one

There total 1 articles about 6-[[2-(4-chlorophenyl)-2-oxoethyl]thio]-1,5-dihydro-1-phenyl-4H-pyrazolo[3,4-d]pyrimidin-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 36.0%

1,5,6,7-tetrahydro-1-phenyl-6-thioxo-4H-pyrazolo[3,4-d]pyrimidin-4-one monopotassium salt + p-chlorophenacyl chloride (937-20-2) → 6-[[2-(4-chlorophenyl)-2-oxoethyl]thio]-1,5-dihydro-1-phenyl-4H-pyrazolo[3,4-d]pyrimidin-4-one (478247-52-8)

Guidance literature:

In ethanol; for 3h; Reflux;

DOI:10.1155/2017/9729284

Reference yield: 42.0%

6-[[2-(4-chlorophenyl)-2-oxoethyl]thio]-1,5-dihydro-1-phenyl-4H-pyrazolo[3,4-d]pyrimidin-4-one (478247-52-8) → 6-(4-chlorophenyl)-1-phenylpyrazolo[3,4-d]thiazolo[3,2-a]pyrimidin-4(1H)-one (478247-53-9)

Guidance literature:

With sulfuric acid; at 20 ℃; for 96h;

DOI:10.1155/2017/9729284

upstream raw materials:

p-chlorophenacyl chloride

Downstream raw materials:

6-(4-chlorophenyl)-1-phenylpyrazolo[3,4-d]thiazolo[3,2-a]pyrimidin-4(1H)-one