(S)-tert-Butyl (2-oxopyrrolidin-3-yl)carbamate

Base Information

Chemical Name:(S)-tert-Butyl (2-oxopyrrolidin-3-yl)carbamate
CAS No.:92235-34-2
Molecular Formula:C9H16 N2 O3
Molecular Weight:200.238
Hs Code.:2933790090
European Community (EC) Number:802-065-8
DSSTox Substance ID:DTXSID80444342
Nikkaji Number:J1.175.141E
Wikidata:Q72448449
Mol file:92235-34-2.mol

Synonyms:92235-34-2;(S)-tert-Butyl (2-oxopyrrolidin-3-yl)carbamate;(S)-Boc-3-amino-2-pyrrolidinone;(S)-tert-butyl 2-oxopyrrolidin-3-ylcarbamate;tert-butyl N-[(3S)-2-oxopyrrolidin-3-yl]carbamate;(2-OXOPYRROLIDIN-3-(S)-YL)CARBAMIC ACID TERT-BUTYL ESTER;tert-butyl (S)-(2-oxopyrrolidin-3-yl)carbamate;Carbamic acid, [(3S)-2-oxo-3-pyrrolidinyl]-, 1,1-dimethylethyl ester;(S)-3-(Boc-amino)-2-pyrrolidone;(S)-(-)-3-Boc-aminopyrrolidin-2-one;(2-oxopyrrolidin-3-(S)-yl)-carbamic acid tert-butyl ester;[2-oxopyrrolidin-3-(S)-yl]-carbamic acid tert-butyl ester;MFCD03426144;FD1232;(S)-tert-Butyl(2-oxopyrrolidin-3-yl)carbamate;SCHEMBL318672;DTXSID80444342;DVWCHAUBYVZILO-LURJTMIESA-N;BCP19316;AKOS015898060;CS-W007134;DS-3828;AC-29410;(S)-3-(t-butoxycarbonylamino)pyrrolidin-2-one;EN300-3068166;A860133;tert-Butyl [(3S)-2-oxopyrrolidin-3-yl]carbamate;(3S)-3beta-(tert-Butoxycarbonylamino)pyrrolidine-2-one;(2-Oxopyrrolidin-3-(S)-yl) carbamic acid tert-butyl ester;[2-Oxo-pyrrolidin-3(S)-yl]-carbamic acid tert-butyl ester;[2-oxopyrrolidin-3(S)-yl]-carbamic acid tert-butyl ester;2-Methyl-2-propanyl [(3S)-2-oxo-3-pyrrolidinyl]carbamate;(2-Oxo-pyrrolidin-3-(S)-yl)-carbamic acid tert-butyl ester;[2-oxopyrrolidin-3-(S)-yl-]-carbamic acid tert-butyl ester

Suppliers and Price of (S)-tert-Butyl (2-oxopyrrolidin-3-yl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(S)-tert-Butyl(2-oxopyrrolidin-3-yl)carbamate 97%
1g
$ 280.00

ChemScene
tert-Butyl(S)-(2-oxopyrrolidin-3-yl)carbamate
5g
$ 900.00

ChemScene
tert-Butyl(S)-(2-oxopyrrolidin-3-yl)carbamate
250mg
$ 107.00

ChemScene
tert-Butyl(S)-(2-oxopyrrolidin-3-yl)carbamate
100mg
$ 67.00

ChemScene
tert-Butyl(S)-(2-oxopyrrolidin-3-yl)carbamate
1g
$ 269.00

Chemenu
(S)-3-(Boc-amino)-2-pyrrolidone 97%
1g
$ 269.00

Chemenu
(S)-3-(Boc-amino)-2-pyrrolidone 97%
5g
$ 808.00

Chemcia Scientific
(S)-tert-Butyl2-oxopyrrolidin-3-yl-carbamate 97%
5 G
$ 900.00

American Custom Chemicals Corporation
(S)-BOC-3-AMINO-2-PYRROLIDINONE 95.00%
1G
$ 837.38

American Custom Chemicals Corporation
(S)-BOC-3-AMINO-2-PYRROLIDINONE 95.00%
10G
$ 2229.15

Total 25 raw suppliers

Chemical Property of (S)-tert-Butyl (2-oxopyrrolidin-3-yl)carbamate

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:168.0-170.3 °C(Solv: ethyl acetate (141-78-6); ligroine (8032-32-4))
Refractive Index:1.491
Boiling Point:394.033oC at 760 mmHg
PKA:11.05±0.20(Predicted)
Flash Point:192.105oC
PSA：67.43000
Density:1.138g/cm3
LogP:1.11930
Storage Temp.:2-8°C
XLogP3:0.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:200.11609238
Heavy Atom Count:14
Complexity:245

Purity/Quality:

97% ^*data from raw suppliers

(S)-tert-Butyl(2-oxopyrrolidin-3-yl)carbamate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC1CCNC1=O
Isomeric SMILES:CC(C)(C)OC(=O)N[C@H]1CCNC1=O

Technology Process of (S)-tert-Butyl (2-oxopyrrolidin-3-yl)carbamate

There total 2 articles about (S)-tert-Butyl (2-oxopyrrolidin-3-yl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

: 25691-37-6,80445-78-9
(2S)-4-amino-2-[(tert-butoxycarbonyl)amino]butanoic acid

: 92235-34-2
(2-oxopyrrolidin-3-(S)-yl)carbamic acid tert-butyl ester

Guidance literature:: With sodium hydrogencarbonate; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; In N,N-dimethyl-formamide; at 20 ℃; for 12h;

Reference yield:

: 13726-85-7
Boc-Gln-OH

: 25691-37-6,80445-78-9
(2S)-4-amino-2-[(tert-butoxycarbonyl)amino]butanoic acid

: 92235-34-2
(2-oxopyrrolidin-3-(S)-yl)carbamic acid tert-butyl ester

Guidance literature:: With [bis(acetoxy)iodo]benzene; water; In ethyl acetate; acetonitrile; at 10 - 20 ℃;
DOI:10.1080/00397910701693633

Reference yield: 86.0%

: 92235-34-2
(2-oxopyrrolidin-3-(S)-yl)carbamic acid tert-butyl ester

: 186551-90-6
4-(benzhydrylidenylamino)-3-(bromomethyl)benzonitrile

: 186551-91-7
{1-[2-(benzhydrylidenylamino)-5-cyanobenzyl]-2-oxopyrrolidin-3-yl}carbamic acid tert-butyl ester

Guidance literature:: (2-oxopyrrolidin-3-(S)-yl)carbamic acid tert-butyl ester; With sodium hydride; In tetrahydrofuran; N,N-dimethyl-formamide; at 0 ℃; for 0.0833333h;

4-(benzhydrylidenylamino)-3-(bromomethyl)benzonitrile; In tetrahydrofuran; at 0 ℃; for 4h;
DOI:10.1021/jm990041+