Boc-Tyr-D-Met(O)-Phe-Gly-OPfP

Base Information

Chemical Name:Boc-Tyr-D-Met(O)-Phe-Gly-OPfP
CAS No.:138891-17-5
Molecular Formula:C₃₆H₃₉F₅N₄O₉S
Molecular Weight:798.785
Hs Code.:

Synonyms:Boc-Tyr-D-Met(O)-Phe-Gly-OPfP

Suppliers and Price of Boc-Tyr-D-Met(O)-Phe-Gly-OPfP

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Boc-Tyr-D-Met(O)-Phe-Gly-OPfP

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of Boc-Tyr-D-Met(O)-Phe-Gly-OPfP

There total 9 articles about Boc-Tyr-D-Met(O)-Phe-Gly-OPfP which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 32.0%

: 771-61-9
2,3,4,5,6-pentafluorophenol

: 138923-15-6
Boc-Tyr-D-Met(O)-Phe-Gly-OH

: 138891-17-5
Boc-Tyr-D-Met(O)-Phe-Gly-OPfP

Guidance literature:: With dicyclohexyl-carbodiimide; In tetrahydrofuran; at 25 ℃; for 12h;
DOI:10.1248/cpb.39.2734

Reference yield:

: 3978-80-1
Boc-Tyr-OH

: 138891-17-5
Boc-Tyr-D-Met(O)-Phe-Gly-OPfP

Guidance literature:: Multi-step reaction with 5 steps

1: DCC / tetrahydrofuran

2: Et₃N / dimethylformamide / 25 °C

3: 76 percent / 1N NaOH / methanol / 2 h / 0 °C

4: 90 percent / 35percent H₂O₂, AcOH / acetic acid / 1 h / 25 °C

5: 32 percent / DCC / tetrahydrofuran / 12 h / 25 °C

With sodium hydroxide; dihydrogen peroxide; acetic acid; triethylamine; dicyclohexyl-carbodiimide; In tetrahydrofuran; methanol; acetic acid; N,N-dimethyl-formamide;
DOI:10.1248/cpb.39.2734

Reference yield:

: 65559-51-5
L-Phenylalaninyl-glycine methyl ester

: 138891-17-5
Boc-Tyr-D-Met(O)-Phe-Gly-OPfP

Guidance literature:: Multi-step reaction with 6 steps

1: 2) Et₃N / 1) mixed anhydride, 2) DMF, 1.5 h, ice-cooling

2: anisole, ethanedithiol, CF₃CO₂H

3: Et₃N / dimethylformamide / 25 °C

4: 76 percent / 1N NaOH / methanol / 2 h / 0 °C

5: 90 percent / 35percent H₂O₂, AcOH / acetic acid / 1 h / 25 °C

6: 32 percent / DCC / tetrahydrofuran / 12 h / 25 °C

With ethandithiol; sodium hydroxide; dihydrogen peroxide; acetic acid; methoxybenzene; triethylamine; dicyclohexyl-carbodiimide; trifluoroacetic acid; In tetrahydrofuran; methanol; acetic acid; N,N-dimethyl-formamide;
DOI:10.1248/cpb.39.2734