2-(tert-butyldimethylsilyl)-3,5-bis(methoxymethoxy)phenyl triflate

Base Information

• Chemical Name: 2-(tert-butyldimethylsilyl)-3,5-bis(methoxymethoxy)phenyl triflate
• CAS No.: 1236971-45-1
• Molecular Formula: C₁₇H₂₇F₃O₇SSi
• Molecular Weight: 460.544
• Mol file: 1236971-45-1.mol

Synonyms:2-(tert-butyldimethylsilyl)-3,5-bis(methoxymethoxy)phenyl triflate

Chemical Property of 2-(tert-butyldimethylsilyl)-3,5-bis(methoxymethoxy)phenyl triflate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 2-(tert-butyldimethylsilyl)-3,5-bis(methoxymethoxy)phenyl triflate

There total 1 articles about 2-(tert-butyldimethylsilyl)-3,5-bis(methoxymethoxy)phenyl triflate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

2-(tert-butyldimethylsilyl)-3,5-bis(tert-butyldimethylsilyloxy)phenyl triflate (1236971-43-9) + chloromethyl methyl ether (107-30-2) → 2-(tert-butyldimethylsilyl)-3,5-bis(methoxymethoxy)phenyl triflate (1236971-45-1)

Guidance literature:

With potassium fluoride; 18-crown-6 ether; In tetrahydrofuran; at -10 ℃; for 24h; Inert atmosphere;

DOI:10.1246/cl.2010.508

Reference yield:

ethyl 3-oxodecanoate (13195-66-9) + 2-(tert-butyldimethylsilyl)-3,5-bis(methoxymethoxy)phenyl triflate (1236971-45-1) → 3,5-di-O-(methoxymethyl)cytosporone B

Guidance literature:

With potassium fluoride; 18-crown-6 ether; In 1,2-dimethoxyethane; at 80 ℃; for 20.5h; regioselective reaction; Inert atmosphere;

DOI:10.1246/cl.2010.508

upstream raw materials:

2-(tert-butyldimethylsilyl)-3,5-bis(tert-butyldimethylsilyloxy)phenyl triflate

chloromethyl methyl ether