benzyl 4-(3,4-difluorophenyl)-2-(6-methylpyrazolo[5,1-b][1,3]thiazol-7-yl)-1,3-thiazole-5-carboxylate

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Chemical Name:benzyl 4-(3,4-difluorophenyl)-2-(6-methylpyrazolo[5,1-b][1,3]thiazol-7-yl)-1,3-thiazole-5-carboxylate
CAS No.:1239504-99-4
Molecular Formula:C₂₃H₁₅F₂N₃O₂S₂
Molecular Weight:467.52
Hs Code.:

Synonyms:benzyl 4-(3,4-difluorophenyl)-2-(6-methylpyrazolo[5,1-b][1,3]thiazol-7-yl)-1,3-thiazole-5-carboxylate

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Chemical Property of benzyl 4-(3,4-difluorophenyl)-2-(6-methylpyrazolo[5,1-b][1,3]thiazol-7-yl)-1,3-thiazole-5-carboxylate

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Technology Process of benzyl 4-(3,4-difluorophenyl)-2-(6-methylpyrazolo[5,1-b][1,3]thiazol-7-yl)-1,3-thiazole-5-carboxylate

There total 1 articles about benzyl 4-(3,4-difluorophenyl)-2-(6-methylpyrazolo[5,1-b][1,3]thiazol-7-yl)-1,3-thiazole-5-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

: 1239504-98-3
benzyl 2-(6-methylpyrazolo[5,1-b][1,3]thiazol-7-yl)-4-{[(trifluoromethyl)sulfonyl]oxy}-1,3-thiazole-5-carboxylate

: 168267-41-2
(3,4-difluorophenyl)boronic acid

: 1239504-99-4
benzyl 4-(3,4-difluorophenyl)-2-(6-methylpyrazolo[5,1-b][1,3]thiazol-7-yl)-1,3-thiazole-5-carboxylate

Guidance literature:: With caesium carbonate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; In 1,2-dimethoxyethane; water; at 80 ℃; for 1h;

Reference yield: 97.0%

: 1239504-99-4
benzyl 4-(3,4-difluorophenyl)-2-(6-methylpyrazolo[5,1-b][1,3]thiazol-7-yl)-1,3-thiazole-5-carboxylate

: 1239505-00-0
4-(3,4-difluorophenyl)-2-(6-methylpyrazolo[5,1-b][1,3]thiazol-7-yl)-1,3-thiazole-5-carboxylic acid

Guidance literature:: benzyl 4-(3,4-difluorophenyl)-2-(6-methylpyrazolo[5,1-b][1,3]thiazol-7-yl)-1,3-thiazole-5-carboxylate; With water; sodium hydroxide; In tetrahydrofuran; methanol; at 70 ℃; for 1h;

With hydrogenchloride; In tetrahydrofuran; methanol; water; at 0 ℃;