3-nitro-4-(pyrrolidin-2-ylmethylamino)benzaldehyde trifluoroacetate

Base Information

Chemical Name:3-nitro-4-(pyrrolidin-2-ylmethylamino)benzaldehyde trifluoroacetate
CAS No.:1575819-71-4
Molecular Formula:C₂HF₃O₂*C₁₂H₁₅N₃O₃
Molecular Weight:363.293
Hs Code.:

Synonyms:3-nitro-4-(pyrrolidin-2-ylmethylamino)benzaldehyde trifluoroacetate

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Chemical Property of 3-nitro-4-(pyrrolidin-2-ylmethylamino)benzaldehyde trifluoroacetate

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Technology Process of 3-nitro-4-(pyrrolidin-2-ylmethylamino)benzaldehyde trifluoroacetate

There total 3 articles about 3-nitro-4-(pyrrolidin-2-ylmethylamino)benzaldehyde trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 42564-51-2
4-fluoro-3-nitrobenzaldehyde

: 1575819-71-4
3-nitro-4-(pyrrolidin-2-ylmethylamino)benzaldehyde trifluoroacetate

Guidance literature:: Multi-step reaction with 2 steps

1: N-ethyl-N,N-diisopropylamine / acetonitrile / 16 h / 20 °C

2: dichloromethane / 1.5 h / 0 - 20 °C

With N-ethyl-N,N-diisopropylamine; In dichloromethane; acetonitrile;

Reference yield:

: 1575819-57-6
tert-butyl 2-((4-formyl-2-nitrophenylamino)methyl)pyrrolidine-1-carboxylate

: 76-05-1
trifluoroacetic acid

: 1575819-71-4
3-nitro-4-(pyrrolidin-2-ylmethylamino)benzaldehyde trifluoroacetate

Guidance literature:: In dichloromethane; at 0 - 20 ℃; for 1.5h;

Reference yield:

: 177911-87-4
tert-butyl 2-(aminomethyl)-pyrrolidine-1-carboxylate

: 1575819-71-4
3-nitro-4-(pyrrolidin-2-ylmethylamino)benzaldehyde trifluoroacetate

Guidance literature:: Multi-step reaction with 2 steps

1: N-ethyl-N,N-diisopropylamine / acetonitrile / 16 h / 20 °C

2: dichloromethane / 1.5 h / 0 - 20 °C

With N-ethyl-N,N-diisopropylamine; In dichloromethane; acetonitrile;