10-Hydroxydec-8-ynoic acid

Base Information

Chemical Name:10-Hydroxydec-8-ynoic acid
CAS No.:92016-00-7
Molecular Formula:C10H16 O3
Molecular Weight:184.235
Hs Code.:
DSSTox Substance ID:DTXSID20577567
Wikidata:Q82467608
Mol file:92016-00-7.mol

Synonyms:92016-00-7;10-HYDROXYDEC-8-YNOIC ACID;10-HYDROXY-8-DECYNOIC ACID;SCHEMBL22555432;DTXSID20577567

Suppliers and Price of 10-Hydroxydec-8-ynoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 10-Hydroxydec-8-ynoic acid

Chemical Property:

PSA：57.53000
LogP:1.40730
XLogP3:1.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:184.109944368
Heavy Atom Count:13
Complexity:197

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C(CCCC(=O)O)CCC#CCO

Technology Process of 10-Hydroxydec-8-ynoic acid

There total 3 articles about 10-Hydroxydec-8-ynoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 30515-28-7
7-bromoheptanoic acid

: 107-19-7
propargyl alcohol

: 92016-00-7
10-hydroxydec-8-ynoic acid

Guidance literature:: propargyl alcohol; With iron(II) nitrate; ammonia; lithium; In tetrahydrofuran; at -33 ℃; for 1h; Inert atmosphere;

7-bromoheptanoic acid; In tetrahydrofuran; at -33 ℃; for 4h; Inert atmosphere;
DOI:10.1002/ejoc.201201442

Reference yield:

: 30515-28-7
7-bromoheptanoic acid

: 60851-89-0
MeLi

: 92016-00-7
10-hydroxydec-8-ynoic acid

Guidance literature:: In tetrahydrofuran; ammonia; at -40 ℃; for 20h;
DOI:10.1016/S0040-4039(01)90422-8

Reference yield:

: 88019-89-0
7-iodoheptanoic acid

: 107-19-7
propargyl alcohol

: 92016-00-7
10-hydroxydec-8-ynoic acid

Guidance literature:: With N,N,N,N,N,N-hexamethylphosphoric triamide; lithium amide; Yield given. Multistep reaction; 1.) liq. NH₃, from -50 deg C to -40 deg C, 0.5 h, 2.) THF, liq. NH₃, a) -33 deg C, 1 h, b) RT, 4 h;