4-(5,5-dimethyl-[1,3,2]dioxaborinan-2-yl)-7-phenyl-1,3-dihydro-isobenzofuran

Base Information

• Chemical Name: 4-(5,5-dimethyl-[1,3,2]dioxaborinan-2-yl)-7-phenyl-1,3-dihydro-isobenzofuran
• CAS No.: 892869-30-6
• Molecular Formula: C₁₉H₂₁BO₃
• Molecular Weight: 308.185
• Mol file: 892869-30-6.mol

Synonyms:4-(5,5-dimethyl-[1,3,2]dioxaborinan-2-yl)-7-phenyl-1,3-dihydro-isobenzofuran

Chemical Property of 4-(5,5-dimethyl-[1,3,2]dioxaborinan-2-yl)-7-phenyl-1,3-dihydro-isobenzofuran

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(5,5-dimethyl-[1,3,2]dioxaborinan-2-yl)-7-phenyl-1,3-dihydro-isobenzofuran

There total 1 articles about 4-(5,5-dimethyl-[1,3,2]dioxaborinan-2-yl)-7-phenyl-1,3-dihydro-isobenzofuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

5,5-dimethyl-2-[3-(3-phenyl-prop-2-ynyloxy)-prop-1-ynyl]-[1,3,2]dioxaborinane + acetylene (74-86-2,25067-58-7) → 4-(5,5-dimethyl-[1,3,2]dioxaborinan-2-yl)-7-phenyl-1,3-dihydro-isobenzofuran (892869-30-6)

Guidance literature:

chloro(1,5-cyclooctadiene)(pentamethylcyclopentadiene)ruthenium(II); In 1,2-dichloro-ethane; at 20 ℃; for 1h;

DOI:10.1016/j.tet.2006.02.068

Reference yield: 50.0%

C14H16I2O2 (903892-43-3) + 4-(5,5-dimethyl-[1,3,2]dioxaborinan-2-yl)-7-phenyl-1,3-dihydro-isobenzofuran (892869-30-6) → C42H38O4

Guidance literature:

With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate; tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; In toluene; at 110 ℃; for 15h;

DOI:10.1021/ja061619p

Reference yield: 37.0%

4-(5,5-dimethyl-[1,3,2]dioxaborinan-2-yl)-7-phenyl-1,3-dihydro-isobenzofuran (892869-30-6) + 7,7'-diiodo-1,3,1',3'-tetrahydro-[4,4']biindenyl-2,2,2',2'-tetracarboxylic acid tetramethyl ester → 7,7'-bis-(7-phenyl-1,3-dihydro-isobenzofuran-4-yl)-1,3,1',3'-tetrahydro-[4,4']biindenyl-2,2,2',2'-tetracarboxylic acid tetramethyl ester

Guidance literature:

With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate; tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; In toluene; at 110 ℃; for 24h;

DOI:10.1021/ja061619p

upstream raw materials:

acetylene