(3R,3aS,7aS)-N-p-tolylsulfonyl-3-hydroxy-3a-(3,4-methylenedioxyphenyl)-2,3,3a,6,7,7a-hexahydroindole

Base Information

Chemical Name:(3R,3aS,7aS)-N-p-tolylsulfonyl-3-hydroxy-3a-(3,4-methylenedioxyphenyl)-2,3,3a,6,7,7a-hexahydroindole
CAS No.:215609-76-0
Molecular Formula:C₂₂H₂₃NO₅S
Molecular Weight:413.494
Hs Code.:

Synonyms:(3R,3aS,7aS)-N-p-tolylsulfonyl-3-hydroxy-3a-(3,4-methylenedioxyphenyl)-2,3,3a,6,7,7a-hexahydroindole

Suppliers and Price of (3R,3aS,7aS)-N-p-tolylsulfonyl-3-hydroxy-3a-(3,4-methylenedioxyphenyl)-2,3,3a,6,7,7a-hexahydroindole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (3R,3aS,7aS)-N-p-tolylsulfonyl-3-hydroxy-3a-(3,4-methylenedioxyphenyl)-2,3,3a,6,7,7a-hexahydroindole

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3R,3aS,7aS)-N-p-tolylsulfonyl-3-hydroxy-3a-(3,4-methylenedioxyphenyl)-2,3,3a,6,7,7a-hexahydroindole

There total 5 articles about (3R,3aS,7aS)-N-p-tolylsulfonyl-3-hydroxy-3a-(3,4-methylenedioxyphenyl)-2,3,3a,6,7,7a-hexahydroindole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

: 215609-75-9
N-((S)-2-Benzo[1,3]dioxol-5-yl-cyclohex-2-enyl)-4-methyl-N-(2-oxo-ethyl)-benzenesulfonamide

: 215609-76-0
(3R,3aS,7aS)-N-p-tolylsulfonyl-3-hydroxy-3a-(3,4-methylenedioxyphenyl)-2,3,3a,6,7,7a-hexahydroindole

Guidance literature:: With 4 A molecular sieve; at 230 - 240 ℃;
DOI:10.1021/jo9815249

Reference yield:

: 40597-44-2
N-(2,2-diethoxy-ethyl)-4-methylbenzenesulfonamide

: 215609-76-0
(3R,3aS,7aS)-N-p-tolylsulfonyl-3-hydroxy-3a-(3,4-methylenedioxyphenyl)-2,3,3a,6,7,7a-hexahydroindole

Guidance literature:: Multi-step reaction with 3 steps

1: (S)-BINAPO / Pd₂dba3*CHCl₃ / tetrahydrofuran / 18 h / Ambient temperature

2: 83 percent / FeCl₃*SiO₂ / acetone / Ambient temperature

3: 59 percent / 4 Angstroem molecular sieves / 230 - 240 °C

With 4 A molecular sieve; silica gel; iron(III) chloride; (S)-1,1'-binaphthalene-2,2'-diylbis(diphenylphosphine oxide); tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; In tetrahydrofuran; acetone;
DOI:10.1021/jo9815249

Reference yield:

: 215609-74-8
2-(3,4-methylenedioxyphenyl)-3-[(methoxycarbonyl)oxy]-1-cyclohexene

: 215609-76-0
(3R,3aS,7aS)-N-p-tolylsulfonyl-3-hydroxy-3a-(3,4-methylenedioxyphenyl)-2,3,3a,6,7,7a-hexahydroindole

Guidance literature:: Multi-step reaction with 3 steps

1: (S)-BINAPO / Pd₂dba3*CHCl₃ / tetrahydrofuran / 18 h / Ambient temperature

2: 83 percent / FeCl₃*SiO₂ / acetone / Ambient temperature

3: 59 percent / 4 Angstroem molecular sieves / 230 - 240 °C

With 4 A molecular sieve; silica gel; iron(III) chloride; (S)-1,1'-binaphthalene-2,2'-diylbis(diphenylphosphine oxide); tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; In tetrahydrofuran; acetone;
DOI:10.1021/jo9815249