1-Aziridinecarboxylic acid, 2-(trimethylsilyl)-, methyl ester

Base Information

• Chemical Name: 1-Aziridinecarboxylic acid, 2-(trimethylsilyl)-, methyl ester
• CAS No.: 91936-00-4
• Molecular Formula: C₇H₁₅NO₂Si
• Molecular Weight: 173.287
• Mol file: 91936-00-4.mol

Synonyms:1-Aziridinecarboxylic acid, 2-(trimethylsilyl)-, methyl ester

Chemical Property of 1-Aziridinecarboxylic acid, 2-(trimethylsilyl)-, methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-Aziridinecarboxylic acid, 2-(trimethylsilyl)-, methyl ester

There total 4 articles about 1-Aziridinecarboxylic acid, 2-(trimethylsilyl)-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

methyl N-(2-chloro-2-trimethylsilyl)ethylcarbamate (91935-99-8) → 1-carbomethoxy-2-trimethylsilylaziridine (91936-00-4)

Guidance literature:

With sodium hydroxide; tetraoctyl ammonium bromide; In hexane; at 25 ℃; for 4h;

DOI:10.1016/0022-328X(84)80248-X

Reference yield: 24.9%

ethenyltrimethylsilane (754-05-2) + azidoformiate de methyle (1516-56-9) → 1-carbomethoxy-2-trimethylsilylaziridine (91936-00-4)

Guidance literature:

for 24h; UV-irradiation;

DOI:10.1039/a905182a

Reference yield:

methyl N-chloro-N-(2-chloro-2-trimethylsilyl)ethylcarbamate (91935-98-7) → 1-carbomethoxy-2-trimethylsilylaziridine (91936-00-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 80 percent / 20percent aq. NaHSO₃ / 3 h / 15 °C

2: 75 percent / NaOH, Oct₄N⁺Br^- / hexane / 4 h / 25 °C

With sodium hydroxide; tetraoctyl ammonium bromide; sodium hydrogensulfite; In hexane;

DOI:10.1016/0022-328X(84)80248-X

upstream raw materials:

methyl N-(2-chloro-2-trimethylsilyl)ethylcarbamate

ethenyltrimethylsilane

azidoformiate de methyle

methyl N-chloro-N-(2-chloro-2-trimethylsilyl)ethylcarbamate