(3R,5R)-5-biphenyl-4-ylmethyl-3-methyl-2-oxo-pyrrolidine-1,3-dicarboxylic acid-1-tert-buty l ester-3-ethyl ester

Base Information

Chemical Name:(3R,5R)-5-biphenyl-4-ylmethyl-3-methyl-2-oxo-pyrrolidine-1,3-dicarboxylic acid-1-tert-buty l ester-3-ethyl ester
CAS No.:1038925-06-2
Molecular Formula:C₂₆H₃₁NO₅
Molecular Weight:437.536
Hs Code.:

Synonyms:(3R,5R)-5-biphenyl-4-ylmethyl-3-methyl-2-oxo-pyrrolidine-1,3-dicarboxylic acid-1-tert-buty l ester-3-ethyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (3R,5R)-5-biphenyl-4-ylmethyl-3-methyl-2-oxo-pyrrolidine-1,3-dicarboxylic acid-1-tert-buty l ester-3-ethyl ester

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Technology Process of (3R,5R)-5-biphenyl-4-ylmethyl-3-methyl-2-oxo-pyrrolidine-1,3-dicarboxylic acid-1-tert-buty l ester-3-ethyl ester

There total 1 articles about (3R,5R)-5-biphenyl-4-ylmethyl-3-methyl-2-oxo-pyrrolidine-1,3-dicarboxylic acid-1-tert-buty l ester-3-ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₅H₂₉NO₅

: C₂₅H₂₉NO₅

: 77-78-1
dimethyl sulfate

: 1038925-06-2
(3R,5R)-5-biphenyl-4-ylmethyl-3-methyl-2-oxo-pyrrolidine-1,3-dicarboxylic acid-1-tert-buty l ester-3-ethyl ester

: 1038925-07-3
(3S,5R)-5-biphenyl-4-ylmethyl-3-methyl-2-oxo-pyrrolidine-1,3-dicarboxylic acid-1-tert-buty l ester-3-ethyl ester

Guidance literature:: In toluene; at 20 ℃; for 1.5h;

Reference yield:

: 1038925-06-2
(3R,5R)-5-biphenyl-4-ylmethyl-3-methyl-2-oxo-pyrrolidine-1,3-dicarboxylic acid-1-tert-buty l ester-3-ethyl ester

: 1038925-07-3
(3S,5R)-5-biphenyl-4-ylmethyl-3-methyl-2-oxo-pyrrolidine-1,3-dicarboxylic acid-1-tert-buty l ester-3-ethyl ester

: 1038925-08-4
(3R,5R)-5-(biphenyl-4-yl)methyl-3-methyl-2-oxopyrrolidine-3-carboxylic acid

: 1038925-09-5
(3S,5R)-5-biphenyl-4-ylmethyl-3-methyl-2-oxopyrrolidine-3-carboxylic acid

Guidance literature:: (3R,5R)-5-biphenyl-4-ylmethyl-3-methyl-2-oxo-pyrrolidine-1,3-dicarboxylic acid-1-tert-buty l ester-3-ethyl ester; (3S,5R)-5-biphenyl-4-ylmethyl-3-methyl-2-oxo-pyrrolidine-1,3-dicarboxylic acid-1-tert-buty l ester-3-ethyl ester; With sodium hydroxide; In water; acetonitrile; at 0 - 20 ℃; for 22h;

With hydrogenchloride; In water;