Methyl 2-[[2-[[2-[(2-hydroxybenzoyl)amino]acetyl]amino]-3-phenylpropanoyl]amino]acetate

Base Information

Chemical Name:Methyl 2-[[2-[[2-[(2-hydroxybenzoyl)amino]acetyl]amino]-3-phenylpropanoyl]amino]acetate
CAS No.:78397-59-8
Molecular Formula:C₂₁H₂₃N₃O₆
Molecular Weight:413.43
Hs Code.:
NSC Number:522619
DSSTox Substance ID:DTXSID90326009

Synonyms:78397-59-8;NSC 522619;NSC522619;DTXSID90326009;NSC-522619;methyl 2-[[2-[[2-[(2-hydroxybenzoyl)amino]acetyl]amino]-3-phenylpropanoyl]amino]acetate

Suppliers and Price of Methyl 2-[[2-[[2-[(2-hydroxybenzoyl)amino]acetyl]amino]-3-phenylpropanoyl]amino]acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Methyl 2-[[2-[[2-[(2-hydroxybenzoyl)amino]acetyl]amino]-3-phenylpropanoyl]amino]acetate

Chemical Property:

Vapor Pressure:7.36E-24mmHg at 25°C
Boiling Point:759.2°C at 760 mmHg
Flash Point:412.9°C
Density:1.291g/cm³
XLogP3:2
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:10
Exact Mass:413.15868546
Heavy Atom Count:30
Complexity:606

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)CNC(=O)C(CC1=CC=CC=C1)NC(=O)CNC(=O)C2=CC=CC=C2O

Technology Process of Methyl 2-[[2-[[2-[(2-hydroxybenzoyl)amino]acetyl]amino]-3-phenylpropanoyl]amino]acetate

There total 4 articles about Methyl 2-[[2-[[2-[(2-hydroxybenzoyl)amino]acetyl]amino]-3-phenylpropanoyl]amino]acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 112716-65-1
N-[N-(2-glycyloxy-benzoyl)-DL-phenylalanyl]-glycine methyl ester; perchlorate

: 78397-59-8
N-salicyloyl-glycyl=>DL-phenylalanyl=>glycine methyl ester

Guidance literature:: With methanol; triethylamine;
DOI:10.1002/hlca.19570400533

Reference yield:

: 3588-57-6
Z-DL-Phe-OH

: 78397-59-8
N-salicyloyl-glycyl=>DL-phenylalanyl=>glycine methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: PCl₃; pyridine

2: palladium/charcoal; aqueous HClO₄; acetic acid / Hydrogenation

3: PCl₃; pyridine / Erwaermen der Reaktionsloesung mit N-Salicyloyl-glycin

With pyridine; palladium on activated charcoal; perchloric acid; acetic acid; phosphorus trichloride;
DOI:10.1002/hlca.19570400533

Reference yield:

: 113895-15-1
N-DL-phenylalanyl-glycine methyl ester; perchlorate

: 78397-59-8
N-salicyloyl-glycyl=>DL-phenylalanyl=>glycine methyl ester

Guidance literature:: With pyridine; phosphorus trichloride; Erwaermen der Reaktionsloesung mit N-Salicyloyl-glycin;
DOI:10.1002/hlca.19570400533