2-(S)-(2-(R)-amino-3-phenyl-propionylamino)-5-nitroguanidino-pentanoic acid (2-naphthalen-1-yl-ethyl)-amide

Base Information

Chemical Name:2-(S)-(2-(R)-amino-3-phenyl-propionylamino)-5-nitroguanidino-pentanoic acid (2-naphthalen-1-yl-ethyl)-amide
CAS No.:406953-54-6
Molecular Formula:C₂₇H₃₃N₇O₄
Molecular Weight:519.604
Hs Code.:

Synonyms:2-(S)-(2-(R)-amino-3-phenyl-propionylamino)-5-nitroguanidino-pentanoic acid (2-naphthalen-1-yl-ethyl)-amide

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Chemical Property of 2-(S)-(2-(R)-amino-3-phenyl-propionylamino)-5-nitroguanidino-pentanoic acid (2-naphthalen-1-yl-ethyl)-amide

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Technology Process of 2-(S)-(2-(R)-amino-3-phenyl-propionylamino)-5-nitroguanidino-pentanoic acid (2-naphthalen-1-yl-ethyl)-amide

There total 1 articles about 2-(S)-(2-(R)-amino-3-phenyl-propionylamino)-5-nitroguanidino-pentanoic acid (2-naphthalen-1-yl-ethyl)-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 406953-53-5
[1-(S)-[4-nitroguanidino-1-(2-naphthalen-1-yl-ethylcarbamoyl)-butylcarbamoyl]-2-(R)-phenyl-ethyl]-carbamic acid tert-butyl ester

: 406953-54-6
2-(S)-(2-(R)-amino-3-phenyl-propionylamino)-5-nitroguanidino-pentanoic acid (2-naphthalen-1-yl-ethyl)-amide

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 24h;

Reference yield:

: 104-53-0
3-phenyl-propionaldehyde

: 406953-54-6
2-(S)-(2-(R)-amino-3-phenyl-propionylamino)-5-nitroguanidino-pentanoic acid (2-naphthalen-1-yl-ethyl)-amide

: 406953-55-7
5-nitroguanidino-2-(S)-[3-phenyl-2-(R)-(3-phenyl-propylamino)-propionylamino]-pentanoic acid (2-naphthalen-1-yl-ethyl)-amide

Guidance literature:: 3-phenyl-propionaldehyde; 2-(S)-(2-(R)-amino-3-phenyl-propionylamino)-5-nitroguanidino-pentanoic acid (2-naphthalen-1-yl-ethyl)-amide; In tetrahydrofuran; at 20 ℃; for 24h; Molecular sieve;

With sodium cyanoborohydride; acetic acid; In tetrahydrofuran; for 24h; pH=5;