1-(2-chlorophenyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline

Base Information

• Chemical Name: 1-(2-chlorophenyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline
• CAS No.: 47136-41-4
• Molecular Formula: C₁₇H₁₈ClNO₂
• Molecular Weight: 303.788
• Mol file: 47136-41-4.mol

Synonyms:1-(2-chloro-phenyl)-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline

Chemical Property of 1-(2-chlorophenyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline

Chemical Property:

Purity/Quality:

1-(2-CHLOROPHENYL)-6,7-DIMETHOXY-1,2,3,4-TETRAHYDROISOQUINOLINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(2-chlorophenyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline

There total 3 articles about 1-(2-chlorophenyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-chloro-benzaldehyde (89-98-5) + 2-(3,4-dimethoxyphenyl)-ethylamine (120-20-7) → 1-(2-chloro-phenyl)-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline (47136-41-4)

Guidance literature:

With phosphoric acid; at 37 ℃;

Reference yield:

(2-chloro-benzylidene)-(3,4-dimethoxy-phenethyl)-amine → 1-(2-chloro-phenyl)-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline (47136-41-4)

Guidance literature:

trifluoroacetic acid; for 4h; Heating;

DOI:10.1016/j.bmcl.2008.02.040

Reference yield:

→ 1-(2-chloro-phenyl)-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline (47136-41-4)

Guidance literature:

1-(2-Chlor-phenyl)-6,7-dimethoxy-3,4-dihydro-isochinolin, NaBH4/Me.;

upstream raw materials:

2-chloro-benzaldehyde

2-(3,4-dimethoxyphenyl)-ethylamine