Technology Process of (2R,4R)-2-azido-4-(benzyloxy)octadecan-1-ol
There total 5 articles about (2R,4R)-2-azido-4-(benzyloxy)octadecan-1-ol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
copper(II) sulfate penta hydrate; triflic azide; potassium carbonate;
In
methanol; dichloromethane; water;
for 12h;
Inert atmosphere;
DOI:10.1021/ml2000802
- Guidance literature:
-
Multi-step reaction with 3 steps
1: sodium tetrahydroborate; nickel dichloride / ethanol / 12 h / 20 °C / Inert atmosphere
2: tetrabutyl ammonium fluoride / tetrahydrofuran / 12 h / 20 °C / Inert atmosphere
3: copper(II) sulfate penta hydrate; triflic azide; potassium carbonate / methanol; dichloromethane; water / 12 h / Inert atmosphere
With
sodium tetrahydroborate; copper(II) sulfate penta hydrate; triflic azide; tetrabutyl ammonium fluoride; potassium carbonate; nickel dichloride;
In
tetrahydrofuran; methanol; ethanol; dichloromethane; water;
DOI:10.1021/ml2000802
- Guidance literature:
-
Multi-step reaction with 5 steps
1: triethylamine / dichloromethane / 12 h / 0 - 20 °C / Inert atmosphere
2: carbon tetrabromide; triphenylphosphine / dichloromethane / 24 h / Inert atmosphere
3: sodium tetrahydroborate; nickel dichloride / ethanol / 12 h / 20 °C / Inert atmosphere
4: tetrabutyl ammonium fluoride / tetrahydrofuran / 12 h / 20 °C / Inert atmosphere
5: copper(II) sulfate penta hydrate; triflic azide; potassium carbonate / methanol; dichloromethane; water / 12 h / Inert atmosphere
With
sodium tetrahydroborate; copper(II) sulfate penta hydrate; carbon tetrabromide; triflic azide; tetrabutyl ammonium fluoride; potassium carbonate; triethylamine; triphenylphosphine; nickel dichloride;
In
tetrahydrofuran; methanol; ethanol; dichloromethane; water;
DOI:10.1021/ml2000802
