C₂₁H₂₁N₄O₇SBr

Base Information

• Chemical Name: C₂₁H₂₁N₄O₇SBr
• CAS No.: 1000612-09-8
• Molecular Formula: C₂₁H₂₁BrN₄O₇S
• Molecular Weight: 553.39
• Mol file: 1000612-09-8.mol

Synonyms:C₂₁H₂₁N₄O₇SBr

Chemical Property of C₂₁H₂₁N₄O₇SBr

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of C₂₁H₂₁N₄O₇SBr

There total 10 articles about C₂₁H₂₁N₄O₇SBr which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

C21H22N4O8S (1000612-08-7) → C21H21N4O7SBr (1000612-09-8)

Guidance literature:

With carbon tetrabromide; triphenylphosphine; at 20 ℃; for 6h;

DOI:10.1055/s-2007-986664

Reference yield:

C17H26Br2N2O4Si (1000612-00-9) → C21H21N4O7SBr (1000612-09-8)

Guidance literature:

Multi-step reaction with 6 steps

1: 94 percent / DIBALH / CH₂Cl₂ / 4 h / -78 °C

2: 97 percent / H₂; Et₃N / Pd/C / methanol; CH₂Cl₂ / 5 h / 20 °C

3: 84 percent / MsCl; DBU / 18 h / 0 °C

4: 50 percent / CaO / CH₂Cl₂ / 18 h / 15 °C

5: 97 percent / Et₃N*3HF / tetrahydrofuran / 12 h / 20 °C

6: 73 percent / CBr₄; PPh₃ / 6 h / 20 °C

With carbon tetrabromide; hydrogen; diisobutylaluminium hydride; methanesulfonyl chloride; 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine tris(hydrogen fluoride); triethylamine; triphenylphosphine; calcium oxide; palladium on activated charcoal; In tetrahydrofuran; methanol; dichloromethane; 6: Appel reaction;

DOI:10.1055/s-2007-986664

Reference yield:

C16H24Br2N2O3Si (1000612-01-0) → C21H21N4O7SBr (1000612-09-8)

Guidance literature:

Multi-step reaction with 5 steps

1: 97 percent / H₂; Et₃N / Pd/C / methanol; CH₂Cl₂ / 5 h / 20 °C

2: 84 percent / MsCl; DBU / 18 h / 0 °C

3: 50 percent / CaO / CH₂Cl₂ / 18 h / 15 °C

4: 97 percent / Et₃N*3HF / tetrahydrofuran / 12 h / 20 °C

5: 73 percent / CBr₄; PPh₃ / 6 h / 20 °C

With carbon tetrabromide; hydrogen; methanesulfonyl chloride; 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine tris(hydrogen fluoride); triethylamine; triphenylphosphine; calcium oxide; palladium on activated charcoal; In tetrahydrofuran; methanol; dichloromethane; 5: Appel reaction;

DOI:10.1055/s-2007-986664

upstream raw materials:

C₂₁H₂₂N₄O₈S

C₂₇H₃₆N₄O₈SSi

C₁₁H₁₂Br₂N₂O₄

C₁₇H₂₆Br₂N₂O₄Si