N-acetyl-sulfanilic acid-[6,7-bis-(4-amino-phenyl)-4-oxo-3,4-dihydro-pteridin-2-ylamide]

Base Information

• Chemical Name: N-acetyl-sulfanilic acid-[6,7-bis-(4-amino-phenyl)-4-oxo-3,4-dihydro-pteridin-2-ylamide]
• CAS No.: 875875-69-7
• Molecular Formula: C₂₆H₂₂N₈O₄S
• Molecular Weight: 542.578
• Mol file: 875875-69-7.mol

Synonyms:N-acetyl-sulfanilic acid-[6,7-bis-(4-amino-phenyl)-4-oxo-3,4-dihydro-pteridin-2-ylamide]

Chemical Property of N-acetyl-sulfanilic acid-[6,7-bis-(4-amino-phenyl)-4-oxo-3,4-dihydro-pteridin-2-ylamide]

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-acetyl-sulfanilic acid-[6,7-bis-(4-amino-phenyl)-4-oxo-3,4-dihydro-pteridin-2-ylamide]

There total 2 articles about N-acetyl-sulfanilic acid-[6,7-bis-(4-amino-phenyl)-4-oxo-3,4-dihydro-pteridin-2-ylamide] which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4,4'-diaminobenzil (29602-15-1) + N-acetyl-sulfanilic acid-(4,5-diamino-6-oxo-1,6-dihydro-pyrimidin-2-ylamide) (724457-54-9) → N-acetyl-sulfanilic acid-[6,7-bis-(4-amino-phenyl)-4-oxo-3,4-dihydro-pteridin-2-ylamide] (875875-69-7)

Guidance literature:

With sodium methylate; ethylene glycol; at 110 - 120 ℃;

DOI:10.1021/ja01644a044

Reference yield:

N-acetyl-sulfanilic acid-(6-amino-5-hydroxyimino-4-oxo-4,5-dihydro-pyrimidin-2-ylamide) → N-acetyl-sulfanilic acid-[6,7-bis-(4-amino-phenyl)-4-oxo-3,4-dihydro-pteridin-2-ylamide] (875875-69-7)

Guidance literature:

Multi-step reaction with 2 steps

1: Na₂S₂O₄

2: sodium methylate; ethylene glycol / 110 - 120 °C

With sodium dithionite; sodium methylate; ethylene glycol;

DOI:10.1021/ja01644a044

Reference yield:

N-acetyl-sulfanilic acid-[6,7-bis-(4-amino-phenyl)-4-oxo-3,4-dihydro-pteridin-2-ylamide] (875875-69-7) → sulfanilic acid-[6,7-bis-(4-amino-phenyl)-4-oxo-3,4-dihydro-pteridin-2-ylamide]

Guidance literature:

With sodium hydroxide;

DOI:10.1021/ja01644a044

upstream raw materials:

4,4'-diaminobenzil

N-acetyl-sulfanilic acid-(4,5-diamino-6-oxo-1,6-dihydro-pyrimidin-2-ylamide)