Technology Process of (S,E)-7-((tert-butyldiphenylsilyl)oxy)-1-(3-nitrophenoxy)hept-2-en-4-ol
There total 3 articles about (S,E)-7-((tert-butyldiphenylsilyl)oxy)-1-(3-nitrophenoxy)hept-2-en-4-ol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
Hoveyda-Grubbs catalyst second generation;
In
toluene;
at 20 ℃;
for 1h;
DOI:10.1002/anie.201107874
- Guidance literature:
-
Multi-step reaction with 2 steps
1: dihydrogen peroxide; sodium hydroxide / diethyl ether; water; ethyl acetate / 0.5 h / -55 - 0 °C
2: Hoveyda-Grubbs catalyst second generation / toluene / 1 h / 20 °C
With
Hoveyda-Grubbs catalyst second generation; dihydrogen peroxide; sodium hydroxide;
In
diethyl ether; water; ethyl acetate; toluene;
DOI:10.1002/anie.201107874
- Guidance literature:
-
Multi-step reaction with 3 steps
1: methanol; (S,S)-[CuCl(C10H6N3(phenyl)2C6H2(CH3)2C(CH3)3)]; sodium t-butanolate / diethyl ether / 14 h / -55 °C
2: dihydrogen peroxide; sodium hydroxide / diethyl ether; water; ethyl acetate / 0.5 h / -55 - 0 °C
3: Hoveyda-Grubbs catalyst second generation / toluene / 1 h / 20 °C
With
methanol; Hoveyda-Grubbs catalyst second generation; (S,S)-[CuCl(C10H6N3(phenyl)2C6H2(CH3)2C(CH3)3)]; dihydrogen peroxide; sodium hydroxide; sodium t-butanolate;
In
diethyl ether; water; ethyl acetate; toluene;
DOI:10.1002/anie.201107874
