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Technology Process of N2-[(2R)-2-(3,5-difluorophenyl)-2-hydroxyacetyl]-N1-[(2R,3S)-4-oxo-2-phenyl-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-L-alaninamide

N2-[(2R)-2-(3,5-difluorophenyl)-2-hydroxyacetyl]-N1-[(2R,3S)-4-oxo-2-phenyl-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-L-alaninamide

Base Information
  • Chemical Name:N2-[(2R)-2-(3,5-difluorophenyl)-2-hydroxyacetyl]-N1-[(2R,3S)-4-oxo-2-phenyl-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-L-alaninamide
  • CAS No.:680229-61-2
  • Molecular Formula:C26H23F2N3O5
  • Molecular Weight:495.483
  • Hs Code.:
N<sub>2</sub>-[(2R)-2-(3,5-difluorophenyl)-2-hydroxyacetyl]-N<sub>1</sub>-[(2R,3S)-4-oxo-2-phenyl-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-L-alaninamide

Synonyms:N2-[(2R)-2-(3,5-difluorophenyl)-2-hydroxyacetyl]-N1-[(2R,3S)-4-oxo-2-phenyl-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-L-alaninamide

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Chemical Property of N2-[(2R)-2-(3,5-difluorophenyl)-2-hydroxyacetyl]-N1-[(2R,3S)-4-oxo-2-phenyl-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-L-alaninamide
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Technology Process of N2-[(2R)-2-(3,5-difluorophenyl)-2-hydroxyacetyl]-N1-[(2R,3S)-4-oxo-2-phenyl-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-L-alaninamide

There total 1 articles about N2-[(2R)-2-(3,5-difluorophenyl)-2-hydroxyacetyl]-N1-[(2R,3S)-4-oxo-2-phenyl-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-L-alaninamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2,3-cis)-3-amino-2-phenyl-2,3-dihydro-1,5-benzoxazepin-4(5H)-one hydrochloride

(2,3-cis)-3-amino-2-phenyl-2,3-dihydro-1,5-benzoxazepin-4(5H)-one hydrochloride

N-[(2R)-2-(3,5-difluorophenyl)-2-hydroxyacetyl]-L-alaninate
680231-80-5

N-[(2R)-2-(3,5-difluorophenyl)-2-hydroxyacetyl]-L-alaninate

N<sub>2</sub>-[(2R)-2-(3,5-difluorophenyl)-2-hydroxyacetyl]-N<sub>1</sub>-[(2R,3S)-4-oxo-2-phenyl-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-L-alaninamide
680229-61-2

N2-[(2R)-2-(3,5-difluorophenyl)-2-hydroxyacetyl]-N1-[(2R,3S)-4-oxo-2-phenyl-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-L-alaninamide

N<sub>2</sub>-[(2R)-2-(3,5-difluorophenyl)-2-hydroxyacetyl]-N<sub>1</sub>-[(2S,3R)-4-oxo-2-phenyl-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-L-alaninamide

N2-[(2R)-2-(3,5-difluorophenyl)-2-hydroxyacetyl]-N1-[(2S,3R)-4-oxo-2-phenyl-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-L-alaninamide

Guidance literature:
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In dichloromethane; at 20 ℃;
upstream raw materials:

N-[(2R)-2-(3,5-difluorophenyl)-2-hydroxyacetyl]-L-alaninate

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