Technology Process of C25H32N2O3
There total 9 articles about C25H32N2O3 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
C19H22N2O;
With
n-butyllithium;
In
tetrahydrofuran;
at -78 ℃;
for 1h;
methyl 2-pentenoate;
In
tetrahydrofuran;
at -78 ℃;
for 2h;
DOI:10.1016/j.tet.2014.05.049
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: sodium hydride / tetrahydrofuran; mineral oil / 1 h / 0 °C
2.1: hydrogenchloride / water / 24 h / Reflux
3.1: formic acid / 20 h / 60 °C
4.1: sodium nitrite; hydrogenchloride / water / 1 h
5.1: lithium aluminium tetrahydride / tetrahydrofuran / 0 °C
6.1: acetic acid / toluene / 0 - 20 °C
7.1: n-butyllithium / tetrahydrofuran / 1 h / -78 °C
7.2: 2 h / -78 °C
With
hydrogenchloride; lithium aluminium tetrahydride; n-butyllithium; formic acid; sodium hydride; acetic acid; sodium nitrite;
In
tetrahydrofuran; water; toluene; mineral oil;
7.2: |Michael Addition;
DOI:10.1016/j.tet.2014.05.049
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: hydrogenchloride / water / 24 h / Reflux
2.1: formic acid / 20 h / 60 °C
3.1: sodium nitrite; hydrogenchloride / water / 1 h
4.1: lithium aluminium tetrahydride / tetrahydrofuran / 0 °C
5.1: acetic acid / toluene / 0 - 20 °C
6.1: n-butyllithium / tetrahydrofuran / 1 h / -78 °C
6.2: 2 h / -78 °C
With
hydrogenchloride; lithium aluminium tetrahydride; n-butyllithium; formic acid; acetic acid; sodium nitrite;
In
tetrahydrofuran; water; toluene;
6.2: |Michael Addition;
DOI:10.1016/j.tet.2014.05.049