methyl O--(2->8)-5-acetamido-4,7,9-tri-O-benzyl-3,5-dideoxy-3-(phenylthio)-D-erythro-β-L-gluco-2-nonulopyranosonate

Base Information

• Chemical Name: methyl O--(2->8)-5-acetamido-4,7,9-tri-O-benzyl-3,5-dideoxy-3-(phenylthio)-D-erythro-β-L-gluco-2-nonulopyranosonate
• CAS No.: 123170-16-1
• Molecular Formula: C₈₅H₉₀N₂O₁₇S₂
• Molecular Weight: 1475.78
• Mol file: 123170-16-1.mol

Synonyms:methyl O--(2->8)-5-acetamido-4,7,9-tri-O-benzyl-3,5-dideoxy-3-(phenylthio)-D-erythro-β-L-gluco-2-nonulopyranosonate

Chemical Property of methyl O--(2->8)-5-acetamido-4,7,9-tri-O-benzyl-3,5-dideoxy-3-(phenylthio)-D-erythro-β-L-gluco-2-nonulopyranosonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl O--(2->8)-5-acetamido-4,7,9-tri-O-benzyl-3,5-dideoxy-3-(phenylthio)-D-erythro-β-L-gluco-2-nonulopyranosonate

There total 2 articles about methyl O--(2->8)-5-acetamido-4,7,9-tri-O-benzyl-3,5-dideoxy-3-(phenylthio)-D-erythro-β-L-gluco-2-nonulopyranosonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C85H90N2O17S2 (123170-16-1) → methyl O--(2->8)-5-acetamido-4,7,9-tri-O-benzyl-3,5-dideoxy-3-(phenylthio)-D-erythro-β-L-gluco-2-nonulopyranosonate (123170-16-1)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In toluene; Yield given; 1) 0 deg c, 2h, 2) RT, 0.5h;

DOI:10.1021/jo00032a601

Reference yield:

potassium thiophenolate (3111-52-2) + C79H85BrN2O17S (123188-10-3,139526-14-0) → C85H90N2O17S2 (123170-16-1)

Guidance literature:

In tetrahydrofuran; tert-butyl alcohol; at 0 ℃; for 2h;

DOI:10.1021/jo00032a601

Reference yield: 84.0%

methyl O--(2->8)-5-acetamido-4,7,9-tri-O-benzyl-3,5-dideoxy-3-(phenylthio)-D-erythro-β-L-gluco-2-nonulopyranosonate (123170-16-1) → methyl O--(2->8)-5-acetamido-4,7,9-tri-O-benzyl-2-chloro-2,3,5-trideoxy-3-(phenylthio)-D-erythro-β-L-gluco-2-nonulopyranosonate (123170-21-8)

Guidance literature:

With tetrachloromethane; (Me₃N)3P; In tetrahydrofuran;

DOI:10.1021/ja00204a028

upstream raw materials:

potassium thiophenolate

C₇₉H₈₅BrN₂O₁₇S

Downstream raw materials:

methyl O--(2->8)-5-acetamido-4,7,9-tri-O-benzyl-2-chloro-2,3,5-trideoxy-3-(phenylthio)-D-erythro-β-L-gluco-2-nonulopyranosonate

C₈₅H₈₉BrN₂O₁₆S₂

methyl O--(2->8)-5-acetamido-4,7,9-tri-O-benzyl-2,3,5-trideoxy-2-fluoro-3-(phenylthio)-D-erythro-β-L-gluco-2-nonulopyranosonate

methyl O--(2->8)-5-acetamido-4,7,9-tri-O-benzyl-2,3,5-trideoxy-2-fluoro-3-(phenylthio)-D-erythro-α-L-gluco-2-nonulopyranosonate