1-(4-(N-tert-butyl-N-[tert-butyldimethylsiloxy]amino)phenyl)pyrrole

Base Information

• Chemical Name: 1-(4-(N-tert-butyl-N-[tert-butyldimethylsiloxy]amino)phenyl)pyrrole
• CAS No.: 916667-67-9
• Molecular Formula: C₂₀H₃₂N₂OSi
• Molecular Weight: 344.572
• Mol file: 916667-67-9.mol

Synonyms:1-(4-(N-tert-butyl-N-[tert-butyldimethylsiloxy]amino)phenyl)pyrrole

Chemical Property of 1-(4-(N-tert-butyl-N-[tert-butyldimethylsiloxy]amino)phenyl)pyrrole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of 1-(4-(N-tert-butyl-N-[tert-butyldimethylsiloxy]amino)phenyl)pyrrole

There total 1 articles about 1-(4-(N-tert-butyl-N-[tert-butyldimethylsiloxy]amino)phenyl)pyrrole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 10.0%

pyrrole (109-97-7,30604-81-0) + 1-[N-tert-butyl-N-(tert-butyldimethylsilyloxy)amino]-4-bromobenzene (168848-31-5) → 1-(4-(N-tert-butyl-N-[tert-butyldimethylsiloxy]amino)phenyl)pyrrole (916667-67-9)

Guidance literature:

With 1,1'-bis-(diphenylphosphino)ferrocene; palladium diacetate; sodium t-butanolate; In toluene; at 110 ℃; for 48h;

DOI:10.1021/jo0616299

Reference yield:

1-(4-(N-tert-butyl-N-[tert-butyldimethylsiloxy]amino)phenyl)pyrrole (916667-67-9) → C14H17N2O

Guidance literature:

Multi-step reaction with 2 steps

1: aq. HCl / aq. ethanol / 20 °C

2: 73 percent / PbO₂ / CH₂Cl₂ / 0.5 h

With hydrogenchloride; lead dioxide; In ethanol; dichloromethane;

DOI:10.1021/jo0616299

upstream raw materials:

pyrrole

1-[N-tert-butyl-N-(tert-butyldimethylsilyloxy)amino]-4-bromobenzene