tert-butyl (2S,3R,4R)-3-acetoxy-4-hydroxy-2-(4-methoxybenzyl)pyrrolidine-1-carboxylate

Base Information

Chemical Name:tert-butyl (2S,3R,4R)-3-acetoxy-4-hydroxy-2-(4-methoxybenzyl)pyrrolidine-1-carboxylate
CAS No.:1225055-48-0
Molecular Formula:C₁₉H₂₇NO₆
Molecular Weight:365.426
Hs Code.:

Synonyms:tert-butyl (2S,3R,4R)-3-acetoxy-4-hydroxy-2-(4-methoxybenzyl)pyrrolidine-1-carboxylate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of tert-butyl (2S,3R,4R)-3-acetoxy-4-hydroxy-2-(4-methoxybenzyl)pyrrolidine-1-carboxylate

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Technology Process of tert-butyl (2S,3R,4R)-3-acetoxy-4-hydroxy-2-(4-methoxybenzyl)pyrrolidine-1-carboxylate

There total 1 articles about tert-butyl (2S,3R,4R)-3-acetoxy-4-hydroxy-2-(4-methoxybenzyl)pyrrolidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 27958-09-4
anisomycin

: 24424-99-5
di-tert-butyl dicarbonate

: 1225055-48-0
tert-butyl (2S,3R,4R)-3-acetoxy-4-hydroxy-2-(4-methoxybenzyl)pyrrolidine-1-carboxylate

Guidance literature:: With triethylamine; In tetrahydrofuran; at 23 ℃; for 15h; Inert atmosphere;
DOI:10.1021/ol100587j

Reference yield: 83.0%

: 1225055-48-0
tert-butyl (2S,3R,4R)-3-acetoxy-4-hydroxy-2-(4-methoxybenzyl)pyrrolidine-1-carboxylate

: 1225055-58-2
tert-butyl (2S,3R,4R)-3-acetoxy-4-hydroxy-2-(3-iodo-4-methoxybenzyl)pyrrolidine-1-carboxylate

Guidance literature:: With indium(III) triflate; N-iodo-succinimide; In acetonitrile; at 23 ℃; for 8h; Inert atmosphere; Darkness;
DOI:10.1021/ol100587j