(S)-methyl 2-(2-(2-(5-fluoro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamido)acetamido)-3-(4-hydroxyphenyl)propanoate

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Chemical Name:(S)-methyl 2-(2-(2-(5-fluoro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamido)acetamido)-3-(4-hydroxyphenyl)propanoate
CAS No.:1191937-54-8
Molecular Formula:C₁₈H₁₉FN₄O₇
Molecular Weight:422.37
Hs Code.:

Synonyms:(S)-methyl 2-(2-(2-(5-fluoro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamido)acetamido)-3-(4-hydroxyphenyl)propanoate

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Chemical Property of (S)-methyl 2-(2-(2-(5-fluoro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamido)acetamido)-3-(4-hydroxyphenyl)propanoate

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Technology Process of (S)-methyl 2-(2-(2-(5-fluoro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamido)acetamido)-3-(4-hydroxyphenyl)propanoate

There total 1 articles about (S)-methyl 2-(2-(2-(5-fluoro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamido)acetamido)-3-(4-hydroxyphenyl)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 104724-48-3
2-(2-(5-fluoro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamido)acetic acid

: 3417-91-2
L-tyrosine methyl ester HCl

: 1191937-54-8
(S)-methyl 2-(2-(2-(5-fluoro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamido)acetamido)-3-(4-hydroxyphenyl)propanoate

Guidance literature:: 2-(2-(5-fluoro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamido)acetic acid; With benzotriazol-1-ol; dicyclohexyl-carbodiimide; In N,N-dimethyl-formamide; at 0 - 20 ℃;

L-tyrosine methyl ester HCl; With triethylamine; In N,N-dimethyl-formamide; for 4h;
DOI:10.3184/030823409X431364